肥胖相关肾疾病的研究进展
Research Progress on Obesity-Associated Kidney Diseases
查看参考文献80篇
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文摘
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肥胖相关肾疾病的发病机制涉及多个方面,主要包括肾素-血管紧张素-醛固酮系统过度激活、胰岛素抵抗、慢性炎症、脂代谢紊乱及肠道微生态失衡等。针对肥胖相关肾疾病的治疗策略主要集中在生活方式的调整、药物治疗、减重手术及粪菌移植等。深入理解肥胖相关肾疾病的危害和明确其发病机制,将有助于未来开发个性化、精准化的预防、诊断和治疗一体化方案。 |
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其他语种文摘
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The pathogenesis of obesity-associated kidney disease (OAKD) involves many aspects,including the overactivation of the renin-angiotensin-aldosterone system,insulin resistance,chronic inflammation,disorder of lipid metabolism and imbalance of gut microecology.Treatment strategies for OAKD focus on lifestyle adjustments,pharmacotherapy,bariatric surgery,and fecal microbiota transplantation.A deeper understanding of the hazards of OAKD and its pathogenesis will contribute to the development of personalized and precise strategies for prevention,diagnosis and treatment of OAKD in the future. |
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来源
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中国医学科学院学报
,2025,47(1):77-85 【核心库】
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DOI
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10.3881/j.issn.1000-503X.16098
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关键词
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肥胖
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肥胖相关肾疾病
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发病机制
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治疗策略
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地址
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1.
上海交通大学医学院附属第六人民医院肾内科, 上海, 201306
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上海交通大学医学院附属第六人民医院普通外科, 上海, 201306
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上海交通大学医学院附属第六人民医院减重代谢外科, 上海, 201306
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首都医科大学附属北京友谊医院减重代谢外科, 北京, 100050
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语种
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中文 |
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文献类型
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综述型 |
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ISSN
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1000-503X |
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学科
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内科学 |
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基金
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国家重点研发计划
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上海市第六人民医院医院管理研究中心医院管理健康联合体科研专项
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文献收藏号
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CSCD:7943515
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80
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