Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula:A Randomized Controlled Trial
查看参考文献18篇
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文摘
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Objective:To evaluate Chinese medicine (CM) formula Bazheng Powder (八正散) as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI).Methods:A randomized double-blinded trial was performed.Eligible female patients with RUTI were recruited from one hospital and two community health centers.By using a blocked randomization scheme,participants were randomized to receive a CM formula (10 herbs) and antibiotics placebo for 4 weeks,or antibiotics for 1 week followed by 3 weeks of placebo and CM formula placebo.Clinical cure rate and microbiological cure and recurrence after treatment were evaluated.Results:A total 122 eligible patients were enrolled,with 61 cases in each group.The clinical cure rate by the intent-to-treatment approach was 90.2% for the CM group and 82.0% for the antibiotics group (P>0.05).Bacteria were cleared from 88.5% (54/61) of patients in the CM group and 82.0% (50/61) in the antibiotics group.The recurrence rate in recovered patients at the 6-month follow-up was 9.1% (5/61) and 14.0 (7/61) in the CM and antibiotics groups,respectively (P>0.05).Conclusion:CM formula Bazheng Powder is a good alternative option for RUTI treatment.(Registration No.NCT01745328). |
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来源
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Chinese Journal of Integrative Medicine
,2019,25(1):16-22 【核心库】
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DOI
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10.1007/s11655-017-2960-4
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关键词
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Chinese medicine
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recurrent urinary tract infection
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randomized control trial
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地址
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Department of Nephrology and Endocrinology,Wangjing Hospital,Chinese Academy of Chinese Medical Science, Beijing, 100102
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Institute of Integrative Medicine,Sun Yat-sen University, Guangzhou, 510275
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Institute of Disease Control and Prevention,Academy of Military Medical Sciences, Beijing, 100071
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College of Animal Science and Veterinary Medicine,Shenyang Agriculture University, Key Laboratory of Zoonosis of Liaoning Province, Shenyang, 110866
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语种
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英文 |
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文献类型
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研究性论文 |
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ISSN
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1672-0415 |
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学科
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中国医学 |
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基金
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Supported by Chinese Academy of Traditional Chinese Medicine Joint Innovation Research Project
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Traditional Chinese Medicine Dominant Disease Clinical Research Project
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Capital Featured Clinical Application and Promotion Project,China
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文献收藏号
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CSCD:6410946
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