老年人的脑可塑性:来自认知训练的证据
The plasticity of aging brain: Evidence from cognitive training
查看参考文献96篇
文摘
|
老年人大脑结构和功能衰退是其认知功能下降的重要原因.然而,老年人的大脑仍然保持了一定的可塑性.随着神经影像技术的发展,大量研究发现认知训练能够对老年人的大脑结构和功能产生积极影响:(1)在脑结构方面,表现为大脑皮层灰质体积增加、白质神经纤维连接增强;(2)在进行认知任务时,表现为脑功能网络发生重组;(3)在静息态脑功能方面,表现为脑自发活动功能性重组以及功能连接增强.未来的认知训练研究需要考察老年人大脑可塑性存在个体差异的多种影响因素,并通过纵向追踪研究来探讨大脑可塑性的保持性和迁移效应. |
其他语种文摘
|
Healthy aging is associated with cognitive impairment, which generally attributed to declines in brain structure and functioning. However, the aging brain retains structural and functional plasticity. With the development of neuroimaging technologies, a large number of brain imaging studies have confirmed that cognitive training positively impacts brain structure and functioning. After training, the aged individuals show:(1) increased structural gray matter volume and integrity of white matter tracts;(2) functional reorganization of brain network when performing cognitive tasks;(3) functional reorganization in intrinsic brain activity and enhancement functional connectivity during resting state. Further studies of cognitive training are required to investigate various factors that influence individual differences of brain plasticity and determine the lasting effects and transfer effects by using longitudinal studies. |
来源
|
心理科学进展
,2018,26(5):846-858 【核心库】
|
DOI
|
10.3724/SP.J.1042.2018.00846
|
关键词
|
认知老化
;
大脑可塑性
;
认知训练
;
功能重组
;
神经成像
|
地址
|
1.
(中国科学院心理研究所)老年心理研究中心, 中国科学院心理健康重点实验室, 北京, 100101
2.
中国科学院大学心理学系, 北京, 100049
|
语种
|
中文 |
文献类型
|
研究性论文 |
ISSN
|
1671-3710 |
学科
|
社会科学总论 |
基金
|
国家自然科学基金项目
;
北京市科委项目
;
中国科学院“率先行动”计划特色研究所项目
;
国家重点研发计划
;
中国科学院心理健康重点实验室
|
文献收藏号
|
CSCD:6252432
|
参考文献 共
96
共5页
|
1.
Allen E A. A baseline for the multivariate comparison of resting-state networks.
Frontiers in Systems Neuroscience,2011,5:2
|
CSCD被引
4
次
|
|
|
|
2.
Andrews-Hanna J R. Disruption of large-scale brain systems in advanced aging.
Neuron,2007,56(5):924-935
|
CSCD被引
26
次
|
|
|
|
3.
Anguera J A. Video game training enhances cognitive control in older adults.
Nature,2013,501(7465):97-101
|
CSCD被引
31
次
|
|
|
|
4.
Bastin C. Cognitive reserve impacts on inter-individual variability in restingstate cerebral metabolism in normal aging.
NeuroImage,2012,63(2):713-722
|
CSCD被引
1
次
|
|
|
|
5.
Belleville S. Training-related brain plasticity in subjects at risk of developing Alzheimer's disease.
Brain,2011,134(6):1623-1634
|
CSCD被引
10
次
|
|
|
|
6.
Belleville S. The pattern and loci of training-induced brain changes in healthy older adults are predicted by the nature of the intervention.
PLoS One,2014,9(8):e102710
|
CSCD被引
5
次
|
|
|
|
7.
Bender A R. Differential aging of cerebral white matter in middle-aged and older adults: A seven-year follow-up.
NeuroImage,2016,125:74-83
|
CSCD被引
1
次
|
|
|
|
8.
Bennett I J. Disconnected aging: Cerebral white matter integrity and age-related differences in cognition.
Neuroscience,2014,276:187-205
|
CSCD被引
5
次
|
|
|
|
9.
Bennett I J. Age-related differences in multiple measures of white matter integrity: A diffusion tensor imaging study of healthy aging.
Human Brain Mapping,2010,31(3):378-390
|
CSCD被引
3
次
|
|
|
|
10.
Biswal B B. Toward discovery science of human brain function.
Proceedings of the National Academy of Sciences of the United States of America,2010,107(10):4734-4739
|
CSCD被引
46
次
|
|
|
|
11.
Braver T S. Flexible neural mechanisms of cognitive control within human prefrontal cortex.
Proceedings of the National Academy of Sciences of the United States of America,2009,106(18):7351-7356
|
CSCD被引
8
次
|
|
|
|
12.
Brehmer Y. Neural correlates of training-related working-memory gains in old age.
NeuroImage,2011,58(4):1110-1120
|
CSCD被引
7
次
|
|
|
|
13.
Buckner R L. The brain's default network.
Annals of the New York Academy of Sciences,2008,1124(1):1-38
|
CSCD被引
188
次
|
|
|
|
14.
Buschkuehl M. Neuronal effects following working memory training.
Developmental Cognitive Neuroscience,2012,2:S167-S179
|
CSCD被引
9
次
|
|
|
|
15.
Cabeza R. Hemispheric asymmetry reduction in older adults: The HAROLD model.
Psychology and Aging,2002,17(1):85-100
|
CSCD被引
26
次
|
|
|
|
16.
Chapman S B. Neural mechanisms of brain plasticity with complex cognitive training in healthy seniors.
Cerebral Cortex,2015,25(2):396-405
|
CSCD被引
8
次
|
|
|
|
17.
Chapman S B. Distinct brain and behavioral benefits from cognitive vs. physical training: A randomized trial in aging adults.
Frontiers in Human Neuroscience,2016,10:338
|
CSCD被引
4
次
|
|
|
|
18.
Cummins T D R. Theta power is reduced in healthy cognitive aging.
International Journal of Psychophysiology,2007,66(1):10-17
|
CSCD被引
1
次
|
|
|
|
19.
Davis S W. Assessing the effects of age on long white matter tracts using diffusion tensor tractography.
NeuroImage,2009,46(2):530-541
|
CSCD被引
3
次
|
|
|
|
20.
Davis S W. Que PASA? The posterior-anterior shift in aging.
Cerebral Cortex,2008,18(5):1201-1209
|
CSCD被引
13
次
|
|
|
|
|