动物性食品中PCBs的生物有效性及人体日暴露评估
Concentrations and bioaccessibility of polychlorinated biphenyls in animal-based food collected from markets in Shanghai and assessment of associated human daily intake
查看参考文献24篇
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文摘
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通过测定上海市售动物性食品中PCBs的浓度和生物有效性,评估该地区PCBs的人体日暴露量.结果表明,不同种类食品中PCBs的浓度在未检出～3734.3pg/g(湿重)之间,3～6氯PCBs为主要同系物.鱼类中PCBs浓度高于畜类、禽类和软体类.鱼类PCBs的浓度水平遵循以下两规律:海水鱼>淡水鱼;肉食性鱼>杂食性鱼>草食性鱼.采用模拟人体胃肠消化过程测得PCBs的生物有效性,由于食品中脂肪含量与PCBs的生物有效性具有显著的线性关系,故可用于计算样品中PCBs的生物有效性.该地区居民每天通过动物性食品摄入的PCBs量为24439.3pg/d,以PCBs的生物有效性计量为5034.5pg/d.对不同暴露源(包括灰尘和大气颗粒物)的分析表明,鱼类是PCBs人体暴露的主要贡献者,约占人体PCBs日暴露的60%. |
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其他语种文摘
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The concentrations and bioaccessibility of PCBs in animal-based food collected from markets in Shanghai were determined.The associated human daily intake of PCBs was estimated.The concentrations of PCBs ranged from lower than limit of detection to 3734.3 pg/g(wet weight).Tri-to hexa-CBs were the predominant congeners.The PCB concentrations in fish were higher than those in livestock,poultry or shellfish.The following sequences of PCB concentrations in fish were observed:seawater fish > freshwater fish;carnivorous fish > omnivorous fish > herbivorous fish.The bioaccessibility of PCBs were determined via simulating the digestion process in human gastrointestinal tract.The fat contents in animal-based food had a significantly linear correlation with the bioaccessibility of PCBs.Thus the bioaccessibility of PCBs was able to be calculated from the fat contents.The human daily intake via ingestion of animal-based food was 24439.3 pg/d,however,it was reduced to 5034.5 pg/d when the bioaccessibility of PCBs was added to the calculation.Fish was the major contributor to human exposure to PCBs,accounting for 60% of the total PCBs intake coming from food,dust and particulates in the air. |
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来源
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中国环境科学
,2011,31(6):1019-1028 【核心库】
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关键词
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多氯联苯
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动物性食品
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模拟胃肠道
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生物有效性
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日暴露
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地址
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上海大学环境与化学工程学院,环境污染与健康研究所, 上海, 200444
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上海大学环境与化学工程学院,上海射线应用研究所, 上海, 200444
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上海大学环境与化学工程学院,环境污染与健康研究所, 中国科学院广州地球化学研究所,有机地球化学国家重点实验室, 上海, 200444
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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1000-6923 |
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学科
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环境保护管理 |
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基金
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国家自然科学基金资助项目
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国家973计划
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上海市重点学科建设项目
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文献收藏号
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CSCD:4226363
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