异生物素及其代谢物在反刍家畜体组织的分泌与排泄机理
Mechanisms of secretion and excretion of xenobiotics and their metabolits in ruminants
查看参考文献39篇
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文摘
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胆汁分泌和尿液排泄是异生物素如芳香族和脂环族化合物排出反刍动物有机体的主要途径.渗透过滤是胆汁分泌的主要机制,离子运输对共轭态异生物素的胆汁分泌具有重要作用,其影响因素主要为代谢物极性、分子量和结构.胆汁分泌促进了异生物素在动物体内持续地进行肠肝循环.肾脏中的分泌排泄过程在肾单位中进行.代谢物的尿液排泄包括3个基本过程:肾小球过滤、肾小管分泌和肾小管再吸收.家畜有机体排出异生物素的其他途径有唾液、乳汁、汗水和气体.家畜对某一特定饲料的采食量以及饲料本身的属性直接影响异生物素经尿液的排泄,以此建立合理的关系模型就可以根据尿液中的排泄量测定或预测家畜的采食量. |
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其他语种文摘
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The main pathways by which body tissues eliminate xenobiotics, such as aromatic and alicylic com-pounds, are biliary secretion and renal excretion. Biliary secretion has an important role in the persistence of xenobiotics within animal tissues by enterohepatic circulation. The major mechanism of bile flow is osmotic fil-tration. For biliary secretion of conjugating xenobiotics, ionic transport is the main form which is influenced by metabolite polarity, compound molecular weight and structrure. The urine excretion process takes place in functional units of the kidney called nephrons and involves three primary processes: glomerular filtration, tubu-lar secretion and tubular reabsorption. Other possible routes of xenobiotic elimination from the animal environ-ment are saliva, milk, sweat and exhaled air. The attributes of feedstuff and the amount of a particular feed consumed by the animal, directly affect the urinary excretion of xenobiotics. If an inference model is set up ac-cordingly, the feed intake of the animal can be measured or predicted. |
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来源
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草业学报
,2005,14(3):50-55 【核心库】
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关键词
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反刍动物
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体组织
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异生物素
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分泌
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排泄
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地址
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1.
中国科学院西北高原生物研究所, 青海, 西宁, 810001
2.
甘肃农业大学草业学院, 甘肃, 兰州, 730070
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北京师范大学资源科学研究所, 北京, 100875
4.
Universidad Nacional de Le Pampa, Argentina
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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1004-5759 |
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学科
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畜牧、动物医学、狩猎、蚕、蜂 |
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基金
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中国科学院“百人计划”项目
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国家教育部高等学校优秀青年教师教学科研奖励计划
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文献收藏号
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CSCD:1990770
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