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Antibacterial Properties of Ti-6Al-4VexCu Alloys

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Ren Ling 1   Ma Zheng 1   Li Mei 2   Zhang Yu 2   Liu Weiqiang 3   Liao Zhenhua 3   Yang Ke 1 *  
文摘 Surgical implant-associated bacterial infection is becoming a serious clinical problem. A series of copper-bearing titanium alloy, Ti-6Al-4V-xCu (x = 1, 3, 5 wt%), were fabricated in the present study in order to reduce the hazard of the bacterial infection problem by means of the strong antibacterial ability of Cu element. The metallography, X-ray diffraction, antibacterial ability, corrosion resistance and cytotoxicity of Ti-6Al-4V-xCu alloys were preliminarily studied with comparison to the commercial medical Ti-6Al-4V alloy. The Tie6Al-4V-xCu alloys showed obvious antibacterial abilities with good corrosion resistance and cytocompatibility, and the antibacterial role was enhanced with increasing Cu content, which has significant potential for clinical applications as surgical implant materials.
来源 Journal of Materials Science & Technology ,2014,30(7):699-705 【核心库】
DOI 10.1016/j.jmst.2013.12.014
关键词 Ti-6Al-4V ; Cu-bearing titanium alloy ; Antibacterial property
地址

1. Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016  

2. Department of Orthopedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, 510010  

3. Research Institute of Tsinghua University in Shenzhen, Shenzhen High-Tech Industrial Estate, Shenzhen, 518057

语种 英文
文献类型 研究性论文
ISSN 1005-0302
学科 金属学与金属工艺
基金 国家973计划 ;  国家自然科学基金 ;  the Basic Research Project of Shenzhen, China
文献收藏号 CSCD:5198039

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引证文献 33

1 Ma Zheng Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy Journal of Materials Science & Technology,2015,31(7):723-732
CSCD被引 22

2 Jin Shujing Bio-Functional Cu Containing Biomaterials: a NewWay to Enhance Bio-Adaption of Biomaterials Journal of Materials Science & Technology,2016,32(9):835-839
CSCD被引 15

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