椭偏光学生物传感器及生物医学应用
Protein Microarray Biosensor Based on Imaging Ellipsometry and Its Biomedical Applications
查看参考文献28篇
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文摘
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椭偏光学生物传感器是识别和检测蛋白质的一种新型的高通量、快速生物分子分析技术.它可以实现无标记多元生物分子自动化检测、静态或动态测量及定性和定量测量等,已应用于生物医学与临床检测等方面,如肿瘤标志蛋白检测、乙肝五项同时检测、蛋白质竞争吸附以及多元蛋白质相互作用动态测量等,显示出了广阔的应用前景. |
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其他语种文摘
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A protein microarray biosensor based on imaging ellipsometry has been developed as a high-throughput and fast technique for protein analysis. As an automatic technique, it has advanced properties such as label-free, multi-protein simultaneous detection, static or kinetic analysis for protein interaction, and qualitative or quantitative analysis. It has been used for the biomedical applications including tumor markers detection , hepatitis B test, protein competitive adsorption and kinetic visualization for protein interactions. It have demonstrated promising potential for further applications in biomedicine. |
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来源
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中国医学科学院学报
,2006,28(4):596-599 【核心库】
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关键词
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椭偏光学显微成像
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蛋白质微阵列
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生物传感器
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蛋白质检测
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地址
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1.
Graduate School of Chinese Academy of Sciences, Beijing, 100080
2.
中国科学院力学研究所, 国家微重力实验室, 北京, 100080
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语种
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中文 |
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文献类型
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综述型 |
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ISSN
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1000-503X |
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学科
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生物化学;生物物理学 |
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基金
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国家自然科学基金
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中国科学院知识创新工程重大项目
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文献收藏号
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CSCD:2419697
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参考文献 共
28
共2页
|
|
1.
靳刚. 蛋白质芯片与其他生物芯片技术.
生物芯片(第2版),2002:210-300
|
CSCD被引
1
次
|
|
|
|
|
2.
Jin G. A biosensor concept based on imaging ellipsometry for visualization of biomolecular interactions.
Analy Biochem,1995,232(1):69-72
|
CSCD被引
10
次
|
|
|
|
|
3.
Jin G. development for visualization of thin transparent layers on silicon substrate.
Rev Sci Instrum,1996,67(8):2930-2936
|
CSCD被引
15
次
|
|
|
|
|
4.
Wang ZH. A label-free multisensing immunosensor based on imaging ellipsometry.
Analy Chem,2003,75(22):6119-6123
|
CSCD被引
6
次
|
|
|
|
|
5.
Wang ZH. Immunobiosensor interface based on physical and chemical immunoglobulin G adsorption onto mixed self-assembled monolayers.
Bioelectrochemistry,2006,69(1):180-186
|
CSCD被引
1
次
|
|
|
|
|
6.
Wang ZH. Silicon surface modification with a mixed silanes layer to immobilized proteins for biosensor with imaging ellipsometry.
Colloids and surfaces B,2004,34(3):173-177
|
CSCD被引
3
次
|
|
|
|
|
7.
Wang ZH. Covalent immobilization of proteins for the biosensor based on imaging ellipsometry.
J Immunol Meth,2004,285(2):237-243
|
CSCD被引
8
次
|
|
|
|
|
8.
Kodadek T. prospects and problems.
Chem Biol,2001,8(2):105-115
|
CSCD被引
13
次
|
|
|
|
|
9.
Templin MF. Protein microarray technology.
Drug Discov Today,2002,7(15):815-822
|
CSCD被引
6
次
|
|
|
|
|
10.
Hofmann O. Three-dimensional microfluidic confinement for efficient sample delivery to biosensor surfaces.
Anal Chem,2002,74(20):5243-5250
|
CSCD被引
1
次
|
|
|
|
|
11.
靳刚. 生物分子吸附膜层的图像显示--光学椭偏显微成像技术应用之一.
测试技术学报,1998,12(3):166-171
|
CSCD被引
10
次
|
|
|
|
|
12.
孟永宏. 倾斜镜面成像的自动调焦方法.
光电工程,2004,31(12):34-37
|
CSCD被引
1
次
|
|
|
|
|
13.
陈涉. 椭偏光学显微成像系统聚焦评价函数的研究.
光学学报,2005,25(7):923-929
|
CSCD被引
5
次
|
|
|
|
|
14.
Zhao ZY. Detection of somatotropin and corticosterone with imaging ellipsometry.
Proc.20th International Conference of the IEEE Engineering in Medicine and Bilogy Society,1998:269-272
|
CSCD被引
1
次
|
|
|
|
|
15.
王战会. 应用椭偏光学显微成像对IL－6与其受体的相互应用的初步观察.
生物工程学报,2002,18(1):99-101
|
CSCD被引
3
次
|
|
|
|
|
16.
Wang CL. Soluble angiopoietin receptor Tie-2 in patients with acute myocardial infarction and its detection by optical protein-chip.
Proteomics,2004,10(9):15-20
|
CSCD被引
1
次
|
|
|
|
|
17.
Zhang HG. optical protein-chip system for clinical application.
Clinical Chemistry,2005,51(6):1038-1040
|
CSCD被引
5
次
|
|
|
|
|
18.
段金柱. 抗SARS人源单链抗体H12的表达及复性.
生物工程学报,2005,21(5):692-697
|
CSCD被引
2
次
|
|
|
|
|
19.
Duan JZ. A human neutralizing antibody against a conformational epitope shared by oligomeric SARS S1protein.
Antiviral Therapy,2006,11(1):117-123
|
CSCD被引
2
次
|
|
|
|
|
20.
Jin G. The development of biosensor with imaging ellipsometry.
26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society,2004:1975-1978
|
CSCD被引
1
次
|
|
|
|
|
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