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超声定量评估非酒精性脂肪肝病肝脏脂肪变性的研究进展
Research Progress of Quantitative Ultrasound Assessment of Liver Steatosis in Non-alcoholic Fatty Liver Disease

查看参考文献39篇

陈洁   张波 *  
文摘 非酒精性脂肪肝病(NAFLD)的发病率不断上升,如不干预可能演变为脂肪性肝炎、肝硬化,甚至发展成肝细胞癌。目前评估NAFLD肝脏脂肪变性严重程度的金标准是肝活检病理,但有创性限制了其成为大面积筛查的手段。近年来磁共振成像相关检查被作为仅次于肝活检的金标准,但仍存在无法大规模应用的缺点。超声具有简便易行、价格低廉、对身体无伤害等优势,有望成为评估NAFLD的重要检查手段。本文总结了受控衰减参数、声衰减成像、超声肝/肾强度比与肝衰减率、背向散射技术定量评估肝脏脂肪变性的研究现状和进展。
其他语种文摘 The incidence of non-alcoholic fatty liver disease (NAFLD) keeps on rise. Without intervention, it may develop to steatohepatitis,cirrhosis,and even hepatocellular carcinoma. Liver biopsy,the gold standard for evaluating the steatosis severity of NAFLD,is invasive and unsuitable for large-scale screening. In recent years,magnetic resonance imaging (MRI) -related examinations have been used as a gold standard only second to liver biopsy,which still have disadvantages in large-scale application. Ultrasound has the advantages of simple operation,low cost,and safety,and may become an important method for accessing NALFD. This review summarizes the current studies about the diagnosis of liver steatosis by quantitative ultrasound assessment,including controlled attenuation parameters,attenuation imaging,ultrasonic liver/kidney intensity ratio and liver attenuation rate,and integrated backscatter.
来源 中国医学科学院学报 ,2021,43(5):827-832 【核心库】
DOI 10.3881/j.issn.1000-503X.12688
关键词 声衰减成像 ; 受控衰减参数 ; 非酒精性脂肪肝病 ; 肝脂肪变性 ; 定量超声
地址

中日友好医院超声医学科, 北京, 100029

语种 中文
文献类型 综述型
ISSN 1000-503X
学科 临床医学
基金 中日友好医院引进人才项目
文献收藏号 CSCD:7089737

参考文献 共 39 共2页

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引证文献 7

1 朱文雁 3台不同厂家3.0T MR设备测量非酒精性脂肪性肝病患者肝脏质子密度脂肪分数的一致性 中国医学影像学杂志,2022,30(2):111-115,128
CSCD被引 5

2 李军汉 CNPY2调控内质网应激PERK/eIF2α通路在有氧运动干预非酒精性脂肪性肝病中的作用 中国运动医学杂志,2022,41(10):783-792
CSCD被引 0 次

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