黄花獐牙菜的化学成分研究
Chemical constituents of Swertia kingii

张海涛 ¹ 张小龙 ¹ 代东海 ² 纪兰菊 ¹ ^*

文摘	目的研究黄花獐牙菜Swertia kingii的化学成分.方法用各种色谱柱方法进行分离纯化, 根据理化性质和波谱解析鉴定其化学结构.结果从黄花獐牙菜中分离到15个化合物, 鉴定了其中的11个化合物, 分别为β-谷甾醇(β-sitosterol, 1)、1, 8-=羟基一3, 7-二甲氧基曲酮(甲基獐牙菜宁, methylswertianirt, 2)、1, 7-二羟基-3, 8-二甲氧基?酮(gentiacaulein, 3)、1, 8-二羟基一3, 5-二甲氧基?酮(印度獐牙菜素, swerchirin, 4)、8-O-β-D吡畘葡萄糖-1, 3, 7一三羟基?酮(8-O-β-D-glucopyranosyl-1, 3, 7-trihydroxanthone, 5)、芒果苷(mangiferin, 7)、1一O-[β--D-吡喃木糖(1--6)-β-D-吡喃葡萄糖]-7-羟基-3, 8-二甲氧基-酮(1-O-[β-D-xylopyranosyl-(1--6)-β-D-glucopyranosyl]-7-hydroxy-3.8-dimethoxyxanthone, 8)、8-O-[β-D-吡喃木糖(1--6)-D-吡喃葡萄糖]-1, 7二羟基3甲氧基?酮(8-0-[β-D-xylopyranosyl-(1--6)-glucopyranosyl]-1, 7-dihydroxy-3-methoxy- xanthone, 9)1-O_β-D-吡喃葡萄糖-7-羟基一 3, 8-二甲氧基?酮(1-O-β-D-glucopyranosyl- 7-hydroxy-3, 8-dimethoxyxanthone, 10)、异荭草苷(isoorientin, 11)、8-O-β-D-吡喃葡萄糖-1, 3, 5-三羟基?酮(8-O-β-D-glucopyranosyl-1, 3, 5-trihydroxanthone, 13).其余4个还在结构鉴定中.结论所有化合物1~11均为首次从该植物中得到
其他语种文摘	Objective To study the chemical constituents from Swertia kingii. Methods The constituents were isolated and purified by column thromatography methods. Their structures were identified on the basis of physiochemical properties and special analysis. Results Fifteen compounds, were obtained from this plant and 11 of them were identified asβ-sitosterol (1), methylswertianin (2), gentiacaulein (3), swerchirin (4), 8-O-β-D-glucopyranosyl-1, 3, 7-trihydroxanthone(5), mangiferin (7), 1-O-[β-Dxylopyranosyl-(1→6)-β-D-glucopyranosyl]-7-hydroxy-3, 8-dimethoxy-xanthon. (8), 8-O-[β-D-xylopyranosyl-(1→6)-glucopyranosyl]-1, 7-dihydroxy-3-methoxy-xanthone (9), 1-O-β-D-glucopyranosyl-7-hydroxy-3, 8-dimethoxyxanthone (10), isoorientin (11), 8-O-β-D-glucopyranosyl-1, 3, 5-trihydroxanthone (13), Four compounds are being identified. Conclusion All compounds are firsl found from this plant
来源	中草药 ,2010,41(9):1430-1432 【核心库】
关键词	黄花獐牙菜 ; ?酮 ; ?酮苷
地址	1. 中国科学院西北高原生物研究所, 青海, 西宁, 810001 2. 青海普兰特药业公司, 青海, 西宁, 810007
语种	中文
文献类型	研究性论文
ISSN	0253-2670
学科	中国医学
基金	青海龙胆科主要药用植物指纹图谱研究
文献收藏号	CSCD:3987564