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靶向超声造影剂BR55的研究进展
Research Progress of Targeted Ultrasound Contrast Agent BR55

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张馨悦 1,2   吕珂 1 *   李建初 1   姜玉新 1   孝梦甦 1  
文摘 BR55是以血管内皮生长因子受体2为靶点的靶向超声造影剂,可用于检测肿瘤新生血管形成提高诊断准确率。国外已有学者应用BR55进行人体超声分子成像,并显示出良好的安全性和耐受性。本文从BR55组成及特性、动物实验及临床应用等方面对BR55在评估肿瘤新生血管的研究进展进行综述。
其他语种文摘 BR55 is an ultrasound contrast agent targeting vascular endothelial growth factor receptor 2,which can be used to detect tumor neovascularization and improve the diagnostic accuracy.Overseas researchers have used BR55 for human ultrasound molecular imaging,which showed good safety and tolerance.We reviewed the research progress on BR55 applied in the evaluation of tumor neovascularization from the composition,characteristics,animal experiments,and clinical studies of BR55.
来源 中国医学科学院学报 ,2022,44(1):118-122 【核心库】
DOI 10.3881/j.issn.1000-503X.12934
关键词 靶向超声造影剂 ; 超声分子成像 ; 血管内皮生长因子受体
地址

1. 中国医学科学院北京协和医学院北京协和医院超声科, 北京, 100730  

2. 北京中医药大学房山医院超声科, 北京, 102488

语种 中文
文献类型 综述型
ISSN 1000-503X
学科 临床医学
基金 国家自然科学基金 ;  中国医学科学院医学与健康科技创新工程
文献收藏号 CSCD:7178359

参考文献 共 29 共2页

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1 陈升 多靶点靶向微泡研究进展概述 中华超声影像学杂志,2023,32(1):46-50
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