AB-BNCT中子靶物理设计分析
Analysis of Physical Design for AB-BNCT Neutron Target
查看参考文献16篇
|
文摘
|
质子加速器适用于为硼中子俘获治疗提供中子源,其中子源强及能谱较反应堆中子源更具可调性。中子靶物理计算分析是加速器中子源设计的基础,为其提供粒子能量、流强等参数需求分析,并为靶体结构尺寸设计、中子慢化和屏蔽分析等提供前端参数。本文利用MCNPX蒙特卡罗程序,通过对质子打靶的中子产额和能谱、靶体能量沉积、打靶后靶材放射性活度和中子出射空间角分布等进行研究,提出能量2.5MeV质子轰击100~200μm锂靶的设计,并用模拟计算数据论证其合理性。该设计中子源在1mA流强质子轰击下,源强可达9.74×10~(11) s~(-1);拟设计15mA、2.5MeV质子束产生的中子源,在治疗过程中靶材放射性活度累积最大值约为1.44×10~(13) Bq。 |
|
其他语种文摘
|
Proton accelerator is an appropriate device for providing neutron source for accelerator-based boron neutron capture therapy (AB-BNCT).The intensity and the spectrum of proton accelerator driven neutron source are more adjustable than reactor neutron source.The physical analysis of neutron target is the premise for an accelerator neutron source design,and it gives requirements of the accelerator parameters,like proton energy and beam current.Besides,it also provides parameters for structural design of neutron target and assembles for shaping and shielding.In this paper,Monte Carlo program MCNPX was used.After analyzing neuron yield,neutron spectrum,energy deposition,radioactivity of the target and neutron emitting angle distribution,an optimized design proposal for the AB-BNCT neutron source was presented as 2.5MeV proton beam bombarding with lithium target of 100μm to 200μm thickness.The neutron source is designed with an intensity of 9.74×10~(11) s~(-1) from per 1mA incident proton. And the current of the proton beam is suggested as 15mA,which will accumulate a radioactivity of the target material within 1.44×10~(13) Bq. |
|
来源
|
原子能科学技术
,2020,54(5):804-810 【核心库】
|
|
DOI
|
10.7538/yzk.2019.youxian.0580
|
|
关键词
|
硼中子俘获治疗
;
中子靶
;
中子产额
;
能量沉积
;
放射性活度
|
|
地址
|
1.
中国科学院上海应用物理研究所, 上海, 201800
2.
中国科学院大学, 北京, 100049
|
|
语种
|
中文 |
|
文献类型
|
研究性论文 |
|
ISSN
|
1000-6931 |
|
学科
|
原子能技术 |
|
基金
|
中国科学院上海应用物理研究所育新计划资助项目
;
中国科学院上海应用物理研究所重大发展专项资助项目
|
|
文献收藏号
|
CSCD:6735406
|
参考文献 共
16
共1页
|
|
1.
Bergueiro J. Development of high intensity ion sources for a tandem-electrostatic-quadrupole facility for accelerator-based boron neutron capture therapy.
Applied Radiation and Isotopes,2011,69(12):1676-1679
|
被引
1
次
|
|
|
|
|
2.
Zonta A. BNCT: A new option against cancer.
Applied Radiation and Isotopes,2008,67(7/8):1-10
|
被引
1
次
|
|
|
|
|
3.
李长楷. 基于加速器~7Li(p,n)反应的硼中子俘获治疗中子源的优化设计.
核技术,2013,36(9):090203
|
被引
1
次
|
|
|
|
|
4.
Blue T E. Accelerator-based epithermal neutron sources for boron neutron capture therapy of brain tumors.
Journal of Neuro-Oncology,2003,62(1/2):19-31
|
被引
7
次
|
|
|
|
|
5.
Green S. Developments in accelerator based boron neutron capture therapy.
Radiation Physics and Chemistry,1998,51(4/6):561-569
|
被引
2
次
|
|
|
|
|
6.
Bayanov B F. Accelerator-based neutron source for the neutron-capture and fast neutron therapy at hospital.
Nuclear Instruments and Methods in Physics Research A,1998,413(2/3):397-426
|
被引
2
次
|
|
|
|
|
7.
Aleynik V. BINP accelerator based epithermal neutron source.
Applied Radiation and Isotopes,2011,69:1635-1638
|
被引
4
次
|
|
|
|
|
8.
Allen D A. A design study for an accelerator-based epithermal neutron beam for BNCT.
Physics in Medicine and Biology,1995,40(5):807-821
|
被引
6
次
|
|
|
|
|
9.
Burlon A A. Optimization of a neutron production target and a beam shaping assembly based on the ~7Li(p,n)~7Be reaction for BNCT.
Nuclear Instruments and Methods in Physics Research B,2005,229(1):144-156
|
被引
2
次
|
|
|
|
|
10.
Burlon A A. Nuclear reactions induced by deuterons and their applicability to skin tumor treatment through BNCT.
Nuclear Instruments and Methods in Physics Research B,2008,266(22):4903-4910
|
被引
1
次
|
|
|
|
|
11.
Capoulat M E. Applicability of the Be-9(d,n)B-10 reaction to AB-BNCT skin and deep tumor treatment.
Applied Radiation and Isotopes,2011,69:1684-1687
|
被引
1
次
|
|
|
|
|
12.
Colonna N. Measurements of low-energy (d,n) reactions for BNCT.
Medical Physics,1999,26(5):793-798
|
被引
2
次
|
|
|
|
|
13.
Lee C L. Thick target neutron yields for the ~7Li(p, n)~7Be reaction near threshold.
Nuclear Instruments and Methods in Physics Research B,1999,152(1):1-11
|
被引
7
次
|
|
|
|
|
14.
Friedman M. Simulation of the neutron spectrum from the ~7Li(p,n) reaction with a liquid-lithium target at Soreq Applied Research Accelerator Facility.
Nuclear Instruments and Methods in Physics Research A,2013,698:117-126
|
被引
2
次
|
|
|
|
|
15.
Esposito J. Be target development for the accelerator-based SPES-BNCT facility at INFN Legnaro.
Applied Radiation and Isotopes,2009,67(7/8):270-273
|
被引
1
次
|
|
|
|
|
16.
Bleuel D L. Designing accelerator-based epithermal neutron beams for boron neutron capture therapy.
Medical Physics,1998,25(9):1725-1734
|
被引
2
次
|
|
|
|
|
了解气象卫星更多信息，请访问