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Recent progress in drug delivery

查看参考文献224篇

文摘 Drug delivery systems(DDS)are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. Its usual purpose to improve the pharmacological activities of therapeutic drugs and to overcome problems such as limited solubility, drug aggregation, low bioavailability, poor biodistribution, lack of selectivity, or to reduce the side effects of therapeutic drugs. During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields, such as pharmaceutical sciences, material sciences and biomedical sciences. This review provides a concise overview of current progress in this research area through its focus on the delivery strategies, construction techniques and specific examples. It is a valuable reference for pharmaceutical scientists who want to learn more about the design of drug delivery systems.
来源 Acta Pharmaceutica Sinica B ,2019,9(6):1145-1162 【核心库】
DOI 10.1016/j.apsb.2019.08.003
关键词 Pharmaceutics ; Drug delivery system ; Basic research ; Application ; Delivery strategy
地址

1. College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715  

2. School of Pharmaceutical Sciences, Peking University, Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems;; State Key Laboratory of Natural and Biomimetic Drugs, Beijing, 100191  

3. West China School of Pharmacy, Sichuan University, Sichuang Key Laboratory of Drug Targeting and Drug Delivery Systems, Chengdu, 610041  

4. Fudan University, Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai, 201203  

5. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203  

6. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016  

7. School of Pharmaceutical Sciences(Shenzhen), Sun Yat-sen University, Guangzhou, 510275  

8. School of Radiation Medicine and Protection, Soochow University, Suzhou, 215123  

9. School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006  

10. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030  

11. Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850

语种 英文
文献类型 研究性论文
ISSN 2211-3835
学科 药学
基金 the Drug Innovation Major Project of China
文献收藏号 CSCD:6627754

参考文献 共 224 共12页

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引证文献 56 篇

1 姚晟瑜 胰岛素口服给药的困境与突破 药学学报,2020,55(7):1549-1561
被引 3 次

2 Shi Zhaoqing pH-Sensitive nanoscale materials as robust drug delivery systems for cancer therapy Chinese Chemical Letters,2020,31(6):1345-1356
被引 8 次

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