超声检测吸烟与颅内动脉狭窄相关性的多中心研究结果分
Correlation between smoking and occurrence of intracranial artery stenosis by ultrasonography:an analysis of multi-center research results
查看参考文献24篇
|
文摘
|
目的分析吸烟与颅内动脉狭窄发生的相关性。方法采用横断面研究纳入2015年6月至2016年5月,全国20家卒中防治基地因短暂性脑缺血发作(TIA)或缺血性卒中住院的患者共10 711例,排除吸烟及戒烟年限不详者76例,最终纳入10 635例患者。应用经颅彩色多普勒超声和(或)经颅多普勒超声检查评估颅内动脉狭窄病变。记录患者脑血管病基本危险因素(年龄、性别、吸烟及年限、是否戒烟及年限、高血压、糖尿病、高脂血症、心房颤动、卒中家族史)。根据患者吸烟年限不同,分为5个组:无吸烟(7 088例)、吸烟时间≤10年(293例)、11 ~ 20年(770例)、21 ~30年(1 185例)、>30年(1 299例)组进行趋势卡方检验。再根据吸烟者中戒烟年限不同,分为4个组:无戒烟组(2 756例)、戒烟时间1 ~10年(587例)、11 ~20年(153例)、> 20年(51例)进行趋势卡方检验。分析不同吸烟年限及吸烟者不同戒烟年限对颅内动脉狭窄发生的影响。结果(1)吸烟者颅内动脉狭窄发生率[40. 4%(1 433 /3 547)]显著高于无吸烟患者[29. 4%(2 085 /7 088)],差异有统计学意义(χ~2 = 128. 850,P < 0. 01),并且吸烟者脑梗死发生率[91. 6%(3 250 /3 547)]显著高于无吸烟者[85. 0%(6 027 /7 088)],差异有统计学意义(χ~2 = 92. 328,P < 0. 01)。吸烟是颅内动脉狭窄的独立危险因素(OR = 1. 603;95% CI:1. 456 ~ 1. 765;P < 0. 01);随着吸烟年限的增长,颅内动脉狭窄检出率逐渐升高(趋势χ~2 = 115. 437,P < 0. 01);≥20年烟龄患者是否戒烟对颅内动脉狭窄的发生率无明显影响(趋势χ~2 = 1. 043,P = 0. 307)。结论吸烟是影响颅内动脉狭窄的独立危险因素,患病风险随着吸烟年限的增加而上升。而长期吸烟者即使戒烟亦不能减轻对颅内动脉狭窄的影响。 |
|
其他语种文摘
|
Objective To analyze the correlation between smoking and occurrence of intracranial artery stenosis. Methods From June 2015 to May 2016,a total of 10 711 inpatients with transient ischemic attack (TIA)or ischemic stroke from 20 basel hospitals of nationwide were enrolled using a cross- sectional study,76 patients with unknown smoking and smoking cessation years were excluded. Finally,a total of 10 635 patients were enrolled. Transcranial color coded sonography and/ or transcranial Doppler were used evaluate the intracranial artery stenosis lesions. The basic risk factors for cerebrovascular disease (age,sex,smoking and smoking years,whether smoking cessation and years,hypertension,diabetes,hyper- lipidemia,atrial fibrillation,and family history of stroke)were recorded. According to the different smoking years,the smoking years were divided into five groups:non-smoking,smoking time ≤10-year,11 to 20 - year,21 to 30-year,and > 30-year groups for trend chi square test. According to the different smoking cessation years in the smokers,the smoking cessation years were divided into four groups:non-cessation, cessation time 1 to 10-year,11 to 20-year,and > 20-year groups for trend chi square test. The effects of different smoking years and different smoking cessation years on the occurrence of intracranial arterial stenosis were analyzed. Results The incidence of intracranial artery stenosis in the smokers (40. 4% [1 433 / 3 547])was significantly higher than that in the non-smoking patients (29. 4% [2 085 /7 088]). There was significant difference (χ~2 =128. 850,P <0. 01),and the incidence of cerebral infarction in the smokers (91. 6% [3 250 /3 547])was significantly higher than the non-smokers (85. 0% [6 027 /7 088]). There was significant difference (χ~2 =92. 328,P <0. 01). Smoking was an independent risk factor for intracranial artery stenosis (OR,1. 603;95% CI 1. 456 -1. 765;P < 0. 01). With the increase of smoking years,the detection rate of intracranial arterial stenosis increased gradually (trend χ~2 =115. 437,P <0. 01). Whether giving up smoking had no significant effect on the incidence of intracranial artery stenosis in patients with ≥20 years of smoking (trend χ~2 = 1. 043,P = 0. 307). Conclusions Smoking is an independent risk factor for affecting intracranial artery stenosis;the risk of disease increases with the number of smoking years. Long-term smokers (≥20 years)cannot reduce the effect on intracranial artery stenosis,even if they give up smoking. |
|
来源
|
中国脑血管病杂志
,2017,14(6):297-301,312 【扩展库】
|
|
DOI
|
10.3969/j.issn.1672-5921.2017.06.004
|
|
关键词
|
脑血管疾病
;
颅内动脉狭窄
;
吸烟
;
经颅多普勒超声
|
|
地址
|
1.
首都医科大学宣武医院血管超声科, 北京, 100053
2.
吉林大学第一医院神经内科
3.
苏州大学附属第一医院超声科
4.
兰州大学第二医院超声科
5.
天津市环湖医院超声科
6.
大连市中心医院超声科
7.
山西医科大学第一医院超声科
8.
洛阳市中心医院神经内科
9.
山东省聊城市人民医院脑科医院超声科
10.
哈尔滨医科大学附属第一医院超声科
11.
安徽省立医院超声科
12.
中国医科大学附属第一医院超声科
13.
包头市中心医院神经内科
14.
福建省立医院超声科
15.
绵阳市中心医院超声科
16.
新疆医科大学第一附属医院超声科
17.
广东省中医院超声科
18.
昆明医科大学第二附属医院神经内科
19.
珠海市人民医院超声科
20.
湖南省脑科医院超声科
|
|
语种
|
中文 |
|
文献类型
|
研究性论文 |
|
ISSN
|
1672-5921 |
|
学科
|
临床医学;神经病学与精神病学 |
|
基金
|
国家卫生计生委脑卒中筛查与防治工程委员会
|
|
文献收藏号
|
CSCD:6000713
|
参考文献 共
24
共2页
|
|
1.
Meschia J F. Guidelines for the primary prevention of stroke:a statement for healthcare professionals from the American Heart Association/American Stroke Association.
Stroke,2014,45(12):3754-3832
|
被引
61
次
|
|
|
|
|
2.
Caplan L R. Race,sex and occlusive cerebrovascular disease:a review.
Stroke,1986,17(4):648-655
|
被引
31
次
|
|
|
|
|
3.
Wong K S. Intracranial stenosis in Chinese patients with acute stroke.
Neurology,1998,50(3):812-813
|
被引
76
次
|
|
|
|
|
4.
Wong L K. Global burden of intracranial atherosclerosis.
Int J Stroke,2006,1(3):158-159
|
被引
55
次
|
|
|
|
|
5.
Sacco R L. Race-ethnicity and determinants of intracranial atherosclerotic cerebral infarction. The Northern Manhattan Stroke Study.
Stroke,1995,26(1):14-20
|
被引
48
次
|
|
|
|
|
6.
杨功焕.
2010年全球成人烟草调查中国报告,2011:8-19
|
被引
3
次
|
|
|
|
|
7.
Mozaffarian D. for American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2015 update:a report from the American Heart Association.
Circulation,2015,131(4):29-322
|
被引
11
次
|
|
|
|
|
8.
中国医师协会超声医师分会.
血管和浅表器官超声检查指南,2011:8-28
|
被引
2
次
|
|
|
|
|
9.
孟秀峰. 经颅多普勒超声诊断大脑中动脉狭窄准确性的研究.
中国脑血管病杂志,2010,7(6):284-289
|
被引
11
次
|
|
|
|
|
10.
周瑛华. 经颅彩色多普勒超声对颅内段椎动脉狭窄血流动力学的评价标准.
中国脑血管病杂志,2015,8(8):397-403
|
被引
6
次
|
|
|
|
|
11.
杨洁. 经颅多普勒超声及经颅彩色多普勒超声评估基底动脉狭窄的准确性研究.
中华医学超声杂志(电子版),2015,4(4):271-277
|
被引
8
次
|
|
|
|
|
12.
陈竺.
全国第三次死因回顾抽样调查报告,2008:10-17
|
被引
26
次
|
|
|
|
|
13.
The SSYLVIA Study Investigators. Stenting of symptomatic atherosclerotic lesions in the vertebral or intracranial arteries (SSYLVIA):study results.
Stroke,2004,35(6):1388-1392
|
被引
12
次
|
|
|
|
|
14.
Barnett H J M. for North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.
N Engl J Med,1991,325(7):445-453
|
被引
316
次
|
|
|
|
|
15.
European Carotid Surgery Trialists' Collaborative Group. Randomised trial of endarterectomy for recently symptomatic carotid stenosis:final results of the MRC European Carotid Surgery Trial (ECST).
Lancet,1998,351(9113):1379-1387
|
被引
69
次
|
|
|
|
|
16.
江国虹. 天津市男性居民吸烟归因死亡的研究江国虹徐忠良王德征李威张辉张颖.
中华流行病学杂志,2014,35(11):1267-1269
|
被引
6
次
|
|
|
|
|
17.
Kim D E. Associations of cigarette smoking with intracranial atherosclerosis in the patients with acute ischemic stroke.
Clin Neurol Neurosurg,2012,114(9):1243-1247
|
被引
5
次
|
|
|
|
|
18.
Sung Y F. Risk factor stratification for intracranial stenosis in Taiwanese patients with cervico-cerebral stenosis.
J Am Heart Assoc,2015,4(12):pii: e002692
|
被引
2
次
|
|
|
|
|
19.
Yamaguchi Y. Facilitated nitration and oxidation of LDL in cigarette smokers.
Eur J Clin Invest,2005,35(3):186-193
|
被引
4
次
|
|
|
|
|
20.
McEvoy J W. Relationship of cigarette smoking with inflammation and subclinical vascular disease:the Multi-Ethnic Study of Atherosclerosis.
Arterioscler Thromb Vasc Biol,2015,35(4):1002-1010
|
被引
5
次
|
|
|
|
|
了解气象卫星更多信息，请访问