帮助 关于我们

返回检索结果

Genetic diversity of coronaviruses in Miniopterus fuliginosus bats

查看参考文献43篇

Du Jiang 1   Yang Li 1   Ren Xianwen 1   Zhang Junpeng 2   Dong Jie 1   Sun Lilian 1   Zhu Yafang 1   Yang Fan 1   Zhang Shuyi 3   Wu Zhiqiang 1 *   Jin Qi 4 *  
文摘 Coronaviruses, such as severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus, pose significant public health threats. Bats have been suggested to act as natural reservoirs for both these viruses, and periodic monitoring of coronaviruses in bats may thus provide important clues about emergent infectious viruses. The Eastern bent-wing bat Miniopterus fuliginosus is distributed extensively throughout China. We therefore analyzed the genetic diversity of coronaviruses in samples of M. fuliginosus collected from nine Chinese provinces during 2011–2013. The only coronavirus genus found was Alphacoronavirus. We established six complete and five partial genomic sequences of alphacoronaviruses, which revealed that they could be divided into two distinct lineages, with close relationships to coronaviruses in Miniopterus magnater and Miniopterus pusillus. Recombination was confirmed by detecting putative breakpoints of Lineage 1 coronaviruses in M. fuliginosus and M. pusillus (Wu et al., 2015), which supported the results of topological and phylogenetic analyses. The established alphacoronavirus genome sequences showed high similarity to other alphacoronaviruses found in other Miniopterus species, suggesting that their transmission in different Miniopterus species may provide opportunities for recombination with different alphacoronaviruses. The genetic information for these novel alphacoronaviruses will improve our understanding of the evolution and genetic diversity of coronaviruses, with potentially important implications for the transmission of human diseases.
来源 Science China. Life Sciences ,2016,59(6):604-614 【核心库】
DOI 10.1007/s11427-016-5039-0
关键词 coronavirus ; Miniopterus fuliginosus ; bat ; co-infection ; recombination
地址

1. Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, MOH Key Laboratory of Systems Biology of Pathogens, Beijing, 100176  

2. Institute of Estuarine and Coastal Research, East China Normal University, State Key Laboratory of Estuarine and Coastal Research, Shanghai, 200062  

3. College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, 110866  

4. Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, MOH Key Laboratory of Systems Biology of Pathogens;;Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, 100176

语种 英文
文献类型 研究性论文
ISSN 1674-7305
学科 基础医学
基金 the PUMC Youth Fund and Fundamental Research Funds for the Central Universities ;  from China, the National Natural Science Foundation of China ;  the National S&T Major Project ;  supported by the Program for Changjiang Scholars and Innovative Research Team in University of China
文献收藏号 CSCD:5712853

参考文献 共 43 共3页

1.  Apweiler R. The InterPro database, an integrated documentation resource for protein families, domains and functional sites. Nucleic Acids Res,2001,29:37-40 被引 18    
2.  Bateman A. The Pfam protein families database. Nucleic Acids Res,2002,30:276-280 被引 31    
3.  Bosch B J. The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex. J Virol,2003,77:8801-8811 被引 37    
4.  Chen L L. ZCURVE_CoV: a new system to recognize protein coding genes in coronavirus genomes, and its applications in analyzing SARS-CoV genomes. Biochem Biophys Res Commun,2003,307:382-388 被引 4    
5.  Chu D K. Genomic characterizations of bat coronaviruses (1A, 1B and HKU8) and evidence for co-infections in Miniopterus bats. J Gen Virol,2008,89:1282-1287 被引 3    
6.  Cui J. Evolutionary relationships between bat coronaviruses and their hosts. Emerg Infect Dis,2007,13:1526-1532 被引 3    
7.  King A M Q. Virus Taxonomy, Classification and Nomenclature of Viruses. Ninth Report of the International Committee on Taxonomy of Viruses, International Union of Microbiological Societies, Virology Division,2011:806-828 被引 1    
8.  Dveksler G S. Cloning of the mouse hepatitis virus (MHV) receptor: expression in humaaan and hamster cell lines confers susceptibility to MHV. J Virol,1991,65:6881-6891 被引 8    
9.  Gonzalez J M. A comparative sequence analysis to revise the current taxonomy of the family Coronaviridae. Arch Virol,2003,148:2207-2235 被引 19    
10.  Graham R L. Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission. J Virol,2010,84:3134-3146 被引 17    
11.  Guindon S. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol,2010,59:307-321 被引 264    
12.  Herrewegh A A. Feline coronavirus type II strains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus. J Virol,1998,72:4508-4514 被引 4    
13.  Holmes K V. Virology. The SARS coronavirus: a postgenomic era. Science,2003,300:1377-1378 被引 15    
14.  Jonassen C M. Molecular identification and characterization of novel coronaviruses infecting graylag geese (Anser anser), feral pigeons (Columbia livia) and mallards (Anas platyrhynchos). J Gen Virol,2005,86:1597-1607 被引 7    
15.  Kosakovsky Pond S L. GARD: a genetic algorithm for recombination detection. Bioinformatics,2006,22:3096-3098 被引 14    
16.  Lai M M. Coronavirus: organization, replication and expression of genome. Annu Rev Microbiol,1990,44:303-333 被引 6    
17.  Lai M M. The molecular biology of coronaviruses. Adv Virus Res,1997,48:1-100 被引 22    
18.  Lai M M C. Coronaviruses. Fields Virology,2001:1163-1185 被引 3    
19.  Lau S K. Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders. J Virol,2012,86:11906-11918 被引 4    
20.  Lau S K. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci USA,2005,102:14040-14045 被引 52    
引证文献 3

1 Zou Xiaohui Simultaneous virus identification and characterization of severe unexplained pneumonia cases using a metagenomics sequencing technique Science China. Life Sciences,2017,60(3):279-286
被引 1

2 Obameso Joseph O The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population: a two-year follow-up Science China. Life Sciences,2017,60(12):1357-1363
被引 1

显示所有3篇文献

论文科学数据集
PlumX Metrics
相关文献

 作者相关
 关键词相关
 参考文献相关

版权所有 ©2008 中国科学院文献情报中心 制作维护:中国科学院文献情报中心
地址:北京中关村北四环西路33号 邮政编码:100190 联系电话:(010)82627496 E-mail:cscd@mail.las.ac.cn 京ICP备05002861号-4 | 京公网安备11010802043238号