珍珠层粉/壳聚糖多孔支架的制备及分析测试
Preparation and Performance Testing of Nacre Powder/Chitosan Porous Scaffolds
查看参考文献18篇
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文摘
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用负压真空冷冻干燥机在-20℃条件下冷冻干燥48 h制备珍珠层粉/壳聚糖复合多孔支架。用扫描电子显微镜(SEM)观察支架表面形貌,通过X射线衍射分析(XRD)、傅里叶红外光谱(FTIR)等手段对材料进行表征测试,检测其降解性能,并将兔骨髓间充质干细胞与支架共培养检测材料细胞毒性。结果表明复合支架具有稳固的三维多孔结构,孔隙率最大至91.64%,孔径在100~300 μm范围,降解性能适宜,且冷冻干燥制备方法对珍珠层粉的结构无明显破坏,并具有良好的生物相容性,有利于细胞的生长。 |
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其他语种文摘
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The nacre powder/chitosan composite scaffolds were prepared with vacuum freeze dryer for 48 h at —20 °C condition. The surface properties and the porosity of the scaffolds were observed by scanning electron microscopy (SEM), X-ray diffraction analysis (XRD), and Fourier transform infrared spectroscopy (FTIR). The degradability of the scaffolds was detected, and the cytotoxicity was tested by co-culturing the stent with the rabbit bone marrow mesenchymal stem cells. The results showed that the nacre powder/chitosan composite scaffold had a solid three-dimensional porous structure with porosity up to 91.64% and pore size ranging between 100 and 300 μm. The degradability of the scaffold was suitable, and the preparation caused no significant damage to the structure of nacre powder. The histocompatibility was predominant and conductive to the growth of cells. |
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来源
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材料导报
,2016,30(1B):38-41 【核心库】
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DOI
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10.11896/j.issn.1005-023X.2016.02.009
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关键词
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珍珠层粉
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壳聚糖
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冷冻干燥
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法多孔支架
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地址
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兰州大学口腔医学院, 兰州, 730000
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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1005-023X |
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学科
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一般工业技术 |
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基金
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甘肃省自然科学基金
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文献收藏号
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CSCD:5631813
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