五羟色胺和多巴胺与攻击行为的关联研究进展
Research progress on the correlations of aggressive behavior with serotonin and dopamine
查看参考文献92篇
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文摘
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五羟色胺(5-HT)和多巴胺(DA)是影响攻击行为的重要神经递质。参与这两种神经递质合成和分解、运输及信号转导等过程的物质均可能影响攻击行为,如影响5-HT 作用的色氨酸、色氨酸羟化酶、单胺氧化酶、5- 羟吲哚乙酸及5-HT 转运体和5-HT受体;影响DA 作用的多巴胺β 羟化酶和儿茶酚胺邻位甲基转移酶以及DA 转运体。未来攻击行为研究,应考虑色氨酸自身代谢、受体亚型及其他单胺类和儿茶酚胺类神经递质的影响。将肠道微生物纳入攻击行为研究也是未来研究的新方向。 |
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其他语种文摘
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Serotonin (5-HT) and dopamine (DA) are important neurotransmitters that affect aggressive behavior. The substances involved in their syntheses, degradation, transport and signal transduction processes may also affect aggressive behavior, such as tryptophan, tryptophan hydroxylase (TPH), monoamine oxidase (MAO), 5-hydroxyindole acetic acid (5-HIAA), 5-HT transporter (5-HTT) and 5-HT receptors that have an influence on the function of 5-HT. Similarly, dopamine β-hydroxylase (DBH), catechol-O-methyltransferase (COMT) and DA transporter (DAT) can affect the function of DA. In the future, tryptophan metabolism, receptor subtypes and other monoamine or catecholamine neurotransmitters should be considered in aggression study. Furthermore, taking the gut microbes into the aggressive behavior study shows a new direction for future research. |
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来源
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生命科学
,2013,25(10):1027-1035 【扩展库】
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关键词
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五羟色胺
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多巴胺
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攻击行为
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肠道微生物
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肠道
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地址
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中国科学院心理研究所行为生物学室, 中国科学院心理健康重点实验室, 北京, 100101
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语种
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中文 |
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文献类型
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综述型 |
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ISSN
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1004-0374 |
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学科
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生理学 |
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基金
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中国科学院心理研究所心理健康重点实验室博士后基金
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文献收藏号
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CSCD:4978791
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参考文献 共
92
共5页
|
|
1.
Berkowitz L.
Aggression: its causes, consequences, and control,1993
|
被引
4
次
|
|
|
|
|
2.
Bushman B J. Is it time to pull the plug on the hostile versus instrumental aggression dichiotomy?.
Psychol Rev,2001,108(1):273-279
|
被引
10
次
|
|
|
|
|
3.
Krug E G. The world report on violence and health.
Lancet,2002,360(9339):1083-1088
|
被引
15
次
|
|
|
|
|
4.
Bezdjian S. The genetic and environmental covariation among psychopathic personality traits, and reactive and proactive aggression in childhood.
Child Dev,2011,82(4):1267-1281
|
被引
2
次
|
|
|
|
|
5.
Birger M. Aggression: the testosterone-serotonin link.
Isr Med Assoc J,2003,5(9):653-658
|
被引
4
次
|
|
|
|
|
6.
Pavlov K. Genetic determinants of aggression and impulsivity in humans.
J Appl Genet,2012,53(1):61-82
|
被引
4
次
|
|
|
|
|
7.
Smolka M N. Catechol-Omethyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex.
J Neurosci,2005,25(4):836-842
|
被引
8
次
|
|
|
|
|
8.
Yu Y Z. Relationship between Levels of Testosterone and Cortisol in Saliva and Aggressive Behaviors of Adolescents.
Biomed Environ Sci,2009,22(1):44-49
|
被引
2
次
|
|
|
|
|
9.
Cases O. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA.
Science,1995,268(5218):1763-1766
|
被引
15
次
|
|
|
|
|
10.
De Almeida R M. Escalated aggressive behavior: dopamine, serotonin and GABA.
Eur J Pharmacol,2005,526(1/3):51-64
|
被引
10
次
|
|
|
|
|
11.
Nelson R J. Neural mechanisms of aggression.
Nat Rev Neurosci,2007,8(7):536-546
|
被引
15
次
|
|
|
|
|
12.
宋欣. 北京未成年人暴力犯罪生物学及其他相关因素的研究.
中国行为医学科学,2003,12(4):428-430
|
被引
3
次
|
|
|
|
|
13.
周朝昀. 攻击行为生物学基础研究现状.
中国行为医学科学,2005,14(5):475-476
|
被引
11
次
|
|
|
|
|
14.
Lesch K P. Impulsivity, aggression, and serotonin: a molecular psychobiological perspective.
Behav Sci Law,2000,18(5):581-604
|
被引
10
次
|
|
|
|
|
15.
Miczek K A. Monoamines, GABA, glutamate, and aggression.
Biol Aggre,2005:114-149
|
被引
1
次
|
|
|
|
|
16.
Bortolato M. The role of the serotonergic system at the interface of aggression and suicide.
Neuroscience,2013,236:160-185
|
被引
9
次
|
|
|
|
|
17.
孔雀. 攻击行为神经机制的研究进展.
现代生物医学进展,2006,6(8):55-58
|
被引
3
次
|
|
|
|
|
18.
Berger M. The expanded biology of serotonin.
Ann Rev Med,2009,60(1):355-366
|
被引
33
次
|
|
|
|
|
19.
Khaliq S. Relationship of brain tryptophan and serotonin in improving cognitive performance in rats.
Pakistan J Pharm Sci,2006,19(1):11-15
|
被引
3
次
|
|
|
|
|
20.
Williams E. Associations between whole-blood serotonin and subjective mood in healthy male volunteers.
Biol Psychol,2006,71(2):171-174
|
被引
1
次
|
|
|
|
|
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