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Gender disparity in early death after ST-elevation myocardial infarction

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文摘 Background Females with acute myocardial infarction (AMI) have a higher risk of adverse outcomes because of receiving less evidence-based medical care. Our aim was to investigate the gender disparity in early death after ST-elevation myocardial infarction (STEMI) in the current era. Methods A total of 1429 consecutive patients with STEMI in the Liaoning district were analyzed. We compared hospital care and cardiac event data by sex for in-patients with acute STEMI within 24 hours of symptom onset. Results In the emergency reperfusion group (n=754), in-hospital mortality occurred in 4.2% of the males and 11.2% of the females (P=0.001). In the non-emergency reperfusion group (n=675), in-hospital mortality occurred in 13.0% of the males and 22.9% of the females (P=0.001). Multivariate Logistic regression analysis revealed female sex as an independent risk factor of death for STEMI patients during hospitalization (OR=1.691, P=0.007). After controlling for patients who died within 24 hr after admission, female sex was no longer an independent risk factor (OR=1.409, P=0.259). Conclusion Female sex was an independent risk factor for in-hospital mortality of STEMI patients, which is explained by an excess of very early deaths.
来源 Chinese Medical Journal ,2013,126(18):3481-3485 【核心库】
DOI 10.3760/cma.j.issn.0366-6999.20130381
关键词 myocardial infarction ; gender ; reperfusion ; mortality
地址

1. Department of Cardiology, First Affiliated Hospital, Dalian Medical University, Liaoning, Dalian, 116011  

2. Department of Geriatrics, First Affiliated Hospital, Dalian Medical University, Liaoning, Dalian, 116011  

3. Department of Cardiology, Dandong Center Hospital, Liaoning, Dandong, 118000  

4. Department of Cardiology, First Affiliated Hospital, China Medical University, Liaoning, Shenyang, 110001

语种 英文
文献类型 研究性论文
ISSN 0366-6999
学科 内科学
基金 supported by a grant from Science and Technology Planning Project of Liaoning Province, China
文献收藏号 CSCD:4928333

参考文献 共 25 共2页

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引证文献 1

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