Resveratrol: botanical origin, pharmacological activity and applications
白藜芦醇的植物来源、药理活性及应用
查看参考文献142篇
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文摘
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In the past decade, resveratrol, one of the best well-known natural small molecules, has been intensely studied and has shown various promising bioactivities. A growing body of studies point out its potential application and suggest that resveratrol, as a natural product, has highly protective effects on several human diseases, with mild side effects. This review summarizes the botanical origin of resveratrol, and highlights a series of valuable therapeutic potentials, focusing on its pharmacological effects as well as its applied uses. |
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其他语种文摘
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在过去的数十年中,白藜芦醇作为一种广为人知的化合物,表现出多种生物活性。大量的研究表明,白藜芦醇作为一种天然产物,不仅具有潜在的应用价值,而且对多种人类疾病有治疗作用且副作用较小。本文综述了白藜芦醇的生物来源、药理作用及临床应用现状。 |
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来源
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Chinese Journal of Natural Medicines
,2013,11(1):1-15 【扩展库】
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关键词
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Resveratrol
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Botanical origin
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Pharmacological effects
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Applications
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地址
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Department of Pharmacology, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Engineering Technology and Research Center for Plant Polyphenols of Liaoning Province, Shenyang, 110016
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语种
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英文 |
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文献类型
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综述型 |
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ISSN
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1672-3651 |
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学科
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药学 |
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基金
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The National Key Scientific Project for New Drug Discovery and Development, China
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文献收藏号
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CSCD:4738648
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参考文献 共
142
共8页
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1.
Borriello A. Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis.
Nutr Metab Cardiovas,2010,20(8):618-625
|
被引
5
次
|
|
|
|
|
2.
Langcake P. A new class of phytoalexins from grapevines.
Cellul Mol Life Sci,1977,33(2):151-152
|
被引
12
次
|
|
|
|
|
3.
Silva M V. Effect of food on the pharmacokinetic profile of trans-resveratrol.
Int J Clin Pharmacol Ther,2008,46(11):564-570
|
被引
4
次
|
|
|
|
|
4.
Ndiaye M. The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges.
Arch Biochem Biophys,2011,508(2):164-170
|
被引
9
次
|
|
|
|
|
5.
Brisdelli F. Resveratrol: A natural polyphenol with multiple chemopreventive properties.
Curr Drug Metab,2009,10(6):530-546
|
被引
20
次
|
|
|
|
|
6.
Li Z. Resveratrol attenuates brain damage in a rat model of focal cerebral ischemia via up-regulation of hippocampal Bcl-2.
Brain Res,2012,1450:16-124
|
被引
1
次
|
|
|
|
|
7.
Chung J H. Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol.
Aging,2012,4(3):144-145
|
被引
1
次
|
|
|
|
|
8.
Jeong J K. Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity.
Neurosci Res,2012,73(2):99-105
|
被引
10
次
|
|
|
|
|
9.
Soleas G J. The world of resveratrol.
Adv Exp Med Biol,2001,492:159-182
|
被引
4
次
|
|
|
|
|
10.
Timmers S. The journey of resveratrol from yeast to human.
Aging,2012,4(3):1-13
|
被引
4
次
|
|
|
|
|
11.
Xu Q. Resveratrol role in cardiovascular and metabolic health and potential mechanisms of action.
Nutr Res,2012,32(9):648-658
|
被引
6
次
|
|
|
|
|
12.
Lyons M. Resveratrol in raw and baked blueberries and bilberries.
J Agric Food Chem,2003,51(20):5867-5870
|
被引
1
次
|
|
|
|
|
13.
Aggarwal B B. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.
Anticancer Res,2004,24(5A):2783-2840
|
被引
40
次
|
|
|
|
|
14.
Gentile C. Antioxidant activity of Sicilian pistachio (Pistacia vera L. var. Bronte) nut extract and its bioactive components.
J Agric Food Chem,2007,55(3):643-648
|
被引
2
次
|
|
|
|
|
15.
Ray P S. The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury.
Free Radical Bio Med,1999,27(1/2):160-169
|
被引
11
次
|
|
|
|
|
16.
Gurusamy N. Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium.
J Cell Mol Med,2010,14(9):2235-2239
|
被引
4
次
|
|
|
|
|
17.
Hattori R. Pharmacological preconditioning with resveratrol: role of nitric oxide.
Am J Physiol Heart Circ Physiol,2002,282(6):1988-1995
|
被引
18
次
|
|
|
|
|
18.
Juric D. Prevention of concentric hypertrophy and diastolic impairment in aortic-banded rats treated with resveratrol.
Am J Physiol-Heart C,2007,292(5):2138-2143
|
被引
4
次
|
|
|
|
|
19.
Csiszar A. Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
Hypertension,2009,54(3):668-675
|
被引
8
次
|
|
|
|
|
20.
Das S. Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI-3-kinase signaling, but does not involve NFκB.
Free Radic Res,2006,40(10):1066-1075
|
被引
6
次
|
|
|
|
|
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