大炭角菌子实体化学成分的研究
Chemical constituents in sporophore of Xylaria euglossa
查看参考文献14篇
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文摘
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目的研究大炭角菌Xylaria euglossa子实体的化学成分。方法通过硅胶、Sephadex LH-20柱色谱分离化合物,运用氢谱、碳谱、二维核磁共振(~1H-~1HCOSY、HMQC、HMBC、NOESY)、高分辨质谱等光谱学方法鉴定化合物结构。结果分离得到10个化合物,分别鉴定为炭角菌酮(1)、3, 9-二羟基-3-甲基-6, 8-二甲氧基-二氢蒽酮(2)、1-羟基-6, 8-二甲氧基-3-甲基蒽醌(3)、炭角菌内酰胺(4)、neoechinulin A(5)、5α, 8α-过氧麦角甾-6, 22-二烯-3β-醇(6)、麦角甾-4, 6, 8(14), 22-四烯-3-酮(7)、22E-麦角甾-7, 22-二烯-3β, 5α, 6β-三醇(8)、棕榈酸(9)、(2S, 2′R, 3S, 4R)-2-(2′-羟基-十八碳酰胺)二十二碳烷-1, 3, 4-三醇(10)。结论所有化合物均为大炭角菌中首次分离得到。其中化合物1和4为新化合物。 |
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其他语种文摘
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Objective To study the chemical constituents in sporophore of Xylaria euglossa. Methods The chemical constituents were isolated by chromatography on repeated silica gel and Sephadex LH-20 columns. Their structures were elucidated by 1H-NMR, 13C-NMR, 2D-NMR (~1H-~1HCOSY, HMQC, HMBC, and NOESY), HR-ESI-MS, and so on. Results Ten compounds were isolated and identified as xylarinone (1), 3, 9-dihydroxy-3-methyl-6, 8-dimethoxy-dihydroanthracenone (2), 1-hydroxy-6, 8-dimethoxy-3- methylanthraquinone (3), xylactam (4), neoechinulin A (5), 5α, 8α-epidioxy-ergosta-6, 22-dien-3β-ol (6), ergosta-4, 6, 8(14), 22- tetraen-3-one (7), 22E-ergosta-7, 22-dien-3β, 5α, 6β-triol (8), palmitic acid (9), and (2S, 2′R, 3S, 4R)-2-(2′-hydroxy-stearamide) docosane-1, 3, 4-triol (10). Conclusion All compounds are isolated from this fungus for the first time. Compounds 1 and 4 are new compounds. |
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来源
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中草药
,2012,43(12):2327-2332 【核心库】
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关键词
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大炭角菌
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子实体
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蒽酮
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炭角菌酮
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炭角菌内酰胺
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地址
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1.
江苏省农业科学院农产品加工所, 江苏, 南京, 210014
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中国科学院昆明植物研究所, 云南, 昆明, 650204
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南京大学生命科学院, 江苏, 南京, 210093
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语种
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中文 |
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ISSN
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0253-2670 |
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学科
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中国医学 |
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基金
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江苏省农业科技自主创新基金
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文献收藏号
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CSCD:4725438
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