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Coexisting ankylosing spondylitis and rheumatoid arthritis: A case report with literature review

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文摘 A 30-year-old female patient with coexisting ankylosing spondylitis and rheumatoid arthritis was diagnosed and treated. The human leukocyte antigen (HLA)-B27 is a predisposing factor of ankylosing spondylitis and HLA-DR4 is a predisposing factor of rheumatoid arthritis. This patient was HLA-B27 and HLA-DR4 positive, and ankylosing spondylitis manifested before rheumatoid arthritis. After disease modifying anti-rheumatic drugs successfully arrested ankylosing spondylitis activity the patient conceived and delivered a healthy baby. One year later, she developed peripheral polyarthritis and was diagnosed with rheumatoid arthritis. We hypothesized that pregnancy may be one of the environmental factors that can activate rheumatoid arthritis, and that disease modifying anti-rheumatic drugs play an important role in keeping the disease under control.
来源 Chinese Medical Journal ,2011,124(20):3430-3432 【核心库】
DOI 10.3760/cma.j.issn.0366-6999.2011.20.042
关键词 Ankylosing spondylitis ; Disease modifying anti-rheumatic drugs ; Rheumatoid arthritis
地址

Department of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Liaoning, Shenyang, 110004

语种 英文
文献类型 研究性论文
ISSN 0366-6999
学科 内科学
文献收藏号 CSCD:4321519

参考文献 共 11 共1页

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