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动物性食品中PCBs的生物有效性及人体日暴露评估
Concentrations and bioaccessibility of polychlorinated biphenyls in animal-based food collected from markets in Shanghai and assessment of associated human daily intake

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李俊岭 1   张东平 1   余应新 1 *   韩姝媛 1   吴明红 2   盛国英 3   傅家谟 3  
文摘 通过测定上海市售动物性食品中PCBs的浓度和生物有效性,评估该地区PCBs的人体日暴露量.结果表明,不同种类食品中PCBs的浓度在未检出~3734.3pg/g(湿重)之间,3~6氯PCBs为主要同系物.鱼类中PCBs浓度高于畜类、禽类和软体类.鱼类PCBs的浓度水平遵循以下两规律:海水鱼>淡水鱼;肉食性鱼>杂食性鱼>草食性鱼.采用模拟人体胃肠消化过程测得PCBs的生物有效性,由于食品中脂肪含量与PCBs的生物有效性具有显著的线性关系,故可用于计算样品中PCBs的生物有效性.该地区居民每天通过动物性食品摄入的PCBs量为24439.3pg/d,以PCBs的生物有效性计量为5034.5pg/d.对不同暴露源(包括灰尘和大气颗粒物)的分析表明,鱼类是PCBs人体暴露的主要贡献者,约占人体PCBs日暴露的60%.
其他语种文摘 The concentrations and bioaccessibility of PCBs in animal-based food collected from markets in Shanghai were determined.The associated human daily intake of PCBs was estimated.The concentrations of PCBs ranged from lower than limit of detection to 3734.3 pg/g(wet weight).Tri-to hexa-CBs were the predominant congeners.The PCB concentrations in fish were higher than those in livestock,poultry or shellfish.The following sequences of PCB concentrations in fish were observed:seawater fish > freshwater fish;carnivorous fish > omnivorous fish > herbivorous fish.The bioaccessibility of PCBs were determined via simulating the digestion process in human gastrointestinal tract.The fat contents in animal-based food had a significantly linear correlation with the bioaccessibility of PCBs.Thus the bioaccessibility of PCBs was able to be calculated from the fat contents.The human daily intake via ingestion of animal-based food was 24439.3 pg/d,however,it was reduced to 5034.5 pg/d when the bioaccessibility of PCBs was added to the calculation.Fish was the major contributor to human exposure to PCBs,accounting for 60% of the total PCBs intake coming from food,dust and particulates in the air.
来源 中国环境科学 ,2011,31(6):1019-1028 【核心库】
关键词 多氯联苯 ; 动物性食品 ; 模拟胃肠道 ; 生物有效性 ; 日暴露
地址

1. 上海大学环境与化学工程学院,环境污染与健康研究所, 上海, 200444  

2. 上海大学环境与化学工程学院,上海射线应用研究所, 上海, 200444  

3. 上海大学环境与化学工程学院,环境污染与健康研究所, 中国科学院广州地球化学研究所,有机地球化学国家重点实验室, 上海, 200444

语种 中文
文献类型 研究性论文
ISSN 1000-6923
学科 环境保护管理
基金 国家自然科学基金资助项目 ;  国家973计划 ;  上海市重点学科建设项目
文献收藏号 CSCD:4226363

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引证文献 10

1 杨国胜 北京市石景山区夏季雨水和大气中PCBs的特征解析 中国环境科学,2012,32(7):1234-1240
被引 8

2 韩景超 城市不同功能区径流中PCBs的污染特征及毒性评价 中国环境科学,2013,33(3):546-552
被引 6

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