A novel cytotoxic neophysalin from Physalis alkekengi var. francheti

Chu Hang Zhang ¹ Zheng Tao Wang ² ^* Yi Ping Yang ² Qi Shi Sun ³ ^*

文摘	A new neophysalin, named 5α-hydroxy-25,27-dihydro-4,7-didehydro-7-deoxyneophysalin A(1), along with three other known neophysalins (2-4) were isolated from the calyxes of Physalis alkekengi L. var.francheti (Mast.) Makino. The structure of 1 was determined by means of ID and 2D NMR, UV, IR and mass spectra. Compound 1 displayed potent cytotoxicities in vitro against PC-3 and LNCaP cell lines.
来源	Chinese Chemical Letters ,2009,20(11):1327-1330 【核心库】
DOI	10.1016/j.cclet.2009.06.005
关键词	Physalis alkekengi vat francheti ; Neophysalin ; Cytotoxicity
地址	1. School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University, Key Laboratory of Standardization of Chinese Medicines of Ministry of Education Institute of Chinese Materia Medica, Liaoning, Shenyang, 110016 2. Shanghai University of Traditional Chinese Medicine, Key Laboratory of Standardization of Chinese Medicines of Ministry of Education Institute of Chinese Materia Medica, Shanghai, 201203 3. School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University, Liaoning, Shenyang, 110016
语种	英文
文献类型	研究性论文
ISSN	1001-8417
学科	化学
文献收藏号	CSCD:3719908

参考文献共 2 共1页

	1. M.Kawai. Tetrahedron,1991,47:2103	被引 1 次
	2. M.Kawai. Bulletin of the Chemical Society of Japan,1993,66:1299	被引 5 次

引证文献 3 篇

1 郭颖锦灯笼的研究进展中药材,2012,35(12):2039-2045
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2 Peng Xifeng Chemical constituents from the fruit calyx of Physalis alkekengi var.francheti Journal of Chinese Pharmaceutical Sciences,2015,24(9):600-606
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