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丙酸对费氏丙酸杆菌生长及脱氧腺苷钴胺素合成的影响
Effects of Propionic Acid on Propionibacterium Freudenreichii Fermentation and Deoxyadenosylcobalamin Synthesis
查看参考文献8篇
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文摘
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通过添加控制丙酸浓度考查了费氏丙酸杆菌发酵生产V_(B_12)的过程中丙酸抑制细胞生长的浓度范围,在此基础上利用树脂对发酵过程中丙酸进行了选择性吸附后细胞的生长和脱氧腺苷钴胺素合成的变化.研究结果表明,丙酸的浓度在10.0 g/L时,对菌体细胞生长产生了明显的抑制.在丙酸浓度积累到10.0 g/L之前,利用树脂对其吸附分离出2.5 g/L的丙酸后,生物量提高了37.5%,脱氧腺苷钴胺素产量提高了50.0%.该实验为实现丙酸的在线分离和丙酸/V_(B_12)高效联产的新型耦合发酵工艺提供了基础. |
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其他语种文摘
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The concentration of propionic acid that restrained the cell growth in the Propionihacterium freudenreichii fermentation was investigated. The effect of adsorption of propionic acid by resins on Propionibacterium freudenreichii growth and vitamin B_12(V_(B_12)) synthesis were also evaluated. The results showed that when propionic acid concentration was 10.0 g/L, the cell growth was obviously restrained. Before propionic acid concentration reached 10.0 g/L and 2.5 g/L propionic acid was absorbed by resins, the cell concentration improved by 37.5% and the yield of deoxyadenosylcobalarnin 50.0%. The experiment provided a reference for propionic acid in-situ separation and propionic acid/V_(B_12) efficient generation coupling new fermentation process. |
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来源
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食品与发酵工业
,2009,35(3):28-31 【核心库】
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关键词
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生物量
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丙酸
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树脂
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脱氧腺苷钴胺素
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地址
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1.
河北大学生命科学学院, 河北, 保定, 071002
2.
中国科学院过程工程研究所, 生化工程国家重点实验室, 北京, 100080
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北京化工大学生命科学与技术学院, 北京, 100029
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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0253-990X |
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学科
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轻工业、手工业、生活服务业 |
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文献收藏号
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CSCD:3509348
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参考文献 共
8
共1页
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1.
Kaiming Ye. Efficent production of vitamin B12 from propionic acid bacteria under periodic variation of dissolved oxygen concentration.
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被引
1
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2.
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被引
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被引
5
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被引
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8.
Zhong Gu. Effects of propionic acid on propi-oncbacteria ferm entation.
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被引
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