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秤钩风中的生物碱成分
Five alkaloids from vine stems of Diploclisia affinis
查看参考文献8篇
文摘
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目的:对防己科秤钩风属植物秤钩风Diploclisiaaffinis干燥的藤茎进行化学成分研究。方法:秤钩风的干燥藤茎用90%乙醇冷浸提取,所得浸膏用水混悬,然后用5%HCl溶液调整pH2,依次用石油醚,氯仿萃取后,将酸水溶液用10%氨水调整pH9。对该碱水溶液用氯仿萃取,即得总碱部分。对总碱采用各种柱色谱进行分离纯化,分离得到的化合物通过波谱数据分析进行结构鉴定。结果:从总碱中分离得到5个生物碱,分别鉴定为:瑞枯灵(reticuline,1),N-降菏叶碱(asimilobine,2),acutumine(3),2,3-二羟基-9,10-二甲氧基四氢原小檗碱(djhydroxyprotoberberine,4),千金藤啶碱(stepholidine,5)。结论:所有化合物均为首次从该种中分离得到。 |
其他语种文摘
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Objective: To study alkaloid constituents of Diploclisia affinis. Method: The air-dried vine stems of D. affinis were extracted with 90% EtOH three times at room temperature. The EtOH extract was suspended in H2O and adjusted to pH 2 with 5% HCl solution. After extracted with petroleum ether and CHCl3 successively, the aqueous, fraction was adjusted to pH 9 with 10% NH3 · H2O and extracted with CHCl3 again to afford the total alkaloids fraction. The compounds were isolated through column chromatography from the total alkaloids fraction. Their structures were determined on the basis of spectral analysis ( MS, 1H-NMR, 13CNMR). Result : Five alkaloids was identified as reticuline ( 1 ) , asimilobine ( 2 ) , acutumine ( 3 ) , dihydroxyprotoberberine (4) , stepholidine (5), were isolated from the vine stems of D. affinis. Conclusion: All the compounds were obtained from D. affinis for the first time. |
来源
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中国中药杂志
,2008,33(21):2503-2505 【核心库】
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关键词
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秤钩风
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防己科
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异喹啉生物碱
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地址
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中国科学院昆明植物研究所, 植物化学与西部植物资源持续利用国家重点实验室, 云南, 昆明, 650204
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语种
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中文 |
文献类型
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研究性论文 |
ISSN
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1001-5302 |
学科
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中国医学 |
文献收藏号
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CSCD:3417549
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