基于生物信息分析的苍术挥发油成分变异及其化学型的划分
Variation Rules and Chemotype Classification of Atractylodes Lancea Essential Oil based on Bio-Information Science
查看参考文献23篇
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文摘
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借鉴生物信息学的思路，收集文献报道的数据资料，在分析不同产地问及同一产地不同个体间苍术挥发油变异的基础上，总结苍术种内挥发油变异特点和规律，并使用聚类分析、主成分分析等多变量分析方法探索苍术种内化学型的划分。结果表明，不同产地及同一产地不同个体间苍术挥发油均有很大变异，苍术挥发油组分及含量变异与地理分布有一定相关性，挥发油中6个主要组分含量从南向北方呈现连续递减。苍术挥发油主要呈现两种化学型，一种是以湖北苍术为代表，主要位于湖北、安徽、陕西、河南南部等地，以茅术醇、（-桉油醇为主要组成．不舍或含极微量苍术酮和芹烷二烯酮，简称湖北苍术型（HBA）；另一种主要以江苏茅山为代表，主要位于江苏、山东、河北、河南北部等北方地区，主要有苍术酮、苍术素为主组成，简称茅山苍术型（MA）。 |
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其他语种文摘
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To study the variation rules and classify the chemotype of Atractylodes lancea （Thunb.） DC. essential oil, we collected A. lancea essential oil data from the literature referring the bioinformatics methods first. Then essential oil among different populations or different individuals in the same population was compared. It was found that, 1 ） there were large varieties in A. lancea essential oil among populations or even among the individuals in the same population, which involve components and its content. 2） total essential oil and the 6 major components in it （elemol, atractylon, hinesol, β-eudesmol, Selina-4 （14）selina, 7 （11）-dienone and atractylodin） varied continuously in different geographical population. Most of the 6 major components in 26 populations increased or decreased gradually from one population to the other except atractylon and Selina-4 （14）selina, 7 （11）-dienone, which were not detected in some population. 3） total essential oil of A. lancea decreased from south to north China. Since the continuous variety, the chemotype of A. lancea essential oil was classified great differently by different researcher. Cluster analysis and principal component analysis were used to classify the chemotype of A. lancea essential oil in this study after continuous variation was found. And it showed that there were mainly two chemotypes of A. lancea essential oil in China. one was Hubei chemotype （HBA）, which distributed in Hubei, Anhui, Shanxi and south of Henan province, and had hinesol and β-eudesmol as the main components, with a little atractylodin and almost without atractylon and selina-4 （14）selina 7（11）-dienone; the other was Mount. Maoshan Chemotype （MA）, which distributed in the north of Jiangsu, Shangdong, Hebei and north of Henan provines, and characterized by atractylon and atractylodin as main components but a little hinesol, β-eudesmol and other components. A. lancea in Mount. Maoshan Jiangsu province were the representation of MA. The total essential oil content of MA was significantly lower than that of HBA. A. lancea in Mount. Dabieshan in Hubei province was due to the HBA, but they had a little unique in the essential oil from the HBA. The essential oil of individuals varied distinctly in Mount. Dabieshan population, for example, the content ratio of hinesol, β-eudesmol, and atraetylodin in different indeviduals from the largest to the least were 4.57, 9.87 and 26.48, respectively. It seemed that the great variation in essential oil had some relation to the high genetic biodiversity. This paper proposed that people should pay more attention to the Mount. Dabieshan A. lancea for the biodiversity conservation. |
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来源
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资源科学
,2008,30(5):770-777 【核心库】
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关键词
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苍术
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化学型
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挥发油
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地理变异
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生物信息学
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地址
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中国中医研究院中药研究所, 北京, 100700
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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1007-7588 |
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学科
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地质学;农作物 |
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基金
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国家973计划
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国家自然科学基金
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国家科技支撑计划项目
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文献收藏号
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CSCD:3296009
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