蔓荆的化学成分研究
Chemical constituents from fruits of Vitex trifolia
查看参考文献17篇
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文摘
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目的 研究蔓荆Vitex trifolia果实的化学成分.方法 蔓荆干燥果实用95%乙醇提取,采用硅胶、Sephadex LH-20、Rp-8、Rp-18柱色谱进行分离纯化,通过波谱分析(MS、~1H-NMR、~(13)C-NMR)鉴定其结构.结果 从蔓荆中分离得到15个化合物,其中6个二萜、2个倍半萜、1个环烯醚萜苷、1个芳香酸、1个蒽酯、1个黄酮、1个木质素和2个甾体,分别鉴定为:vitexilactone(Ⅰ)、previtexilactone(Ⅱ)、abietatriene-3β-ol(Ⅲ)、vitexlactam A(Ⅳ)、vitedoin B(Ⅴ)、vitetrifolin D(Ⅵ)、spathulenol(Ⅶ)、ent-4α,10β-dihydroxyaromadendrane(Ⅷ)、agnuside(Ⅸ)、大黄素甲醚(Ⅹ)、紫花牡荆素(Ⅺ)、对羟基苯甲酸(Ⅻ)、paulownin(ⅩⅢ)、过氧麦角甾醇(ⅩⅣ)、β-谷甾醇(ⅩⅤ).结论 除化合物Ⅰ、Ⅲ、Ⅵ、Ⅸ、Ⅺ、Ⅻ、ⅩⅣ外,其他8个化合物均为首次从该植物中分离得到. |
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其他语种文摘
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Objective To study the chemical constituents from the fruits of Vitex trifolia. Methods The fruits of V. trifolia were extracted with 95% ethanol, and isolated and purified by column chromatography on silica gel, Sephadex LH-20, and Rp-8 and Rp-18 gel. All the compounds were identified based on spectral analyses (including MS, ~1H-NMR, and ~(13)C-NMR). Results Fifteen compounds were isolated from V. trifolia and were characterized as vitexilactone (Ⅰ), previtexilactone (Ⅱ), abietatriene-3β-ol (Ⅲ), vitexlactam A (Ⅳ), vitedoin B (Ⅴ), vitetrifolin D (Ⅵ), spathulenol (Ⅶ), ent-4α, 10β-dihydroxy-aromadendrane (Ⅷ), agnuside (Ⅸ), physcion (Ⅹ), casticin (Ⅺ), p-hydroxybenzoic acid (Ⅹ Ⅱ), paulownin(Ⅹ Ⅲ), ergosterol peroxide (Ⅹ Ⅳ), and β-sitosterols (Ⅹ Ⅴ). Conclusion Except for the compounds Ⅰ, Ⅲ, Ⅵ, Ⅸ, Ⅺ, Ⅹ Ⅱ, and Ⅹ Ⅳ, the other eight compounds are obtained from this plant for the first time. |
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来源
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中草药
,2007,38(5):656-659 【核心库】
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关键词
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蔓荆
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二萜
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木质素
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倍半萜
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环烯醚萜苷
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地址
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中国科学院昆明植物研究所, 植物化学与西部植物资源持续利用国家重点实验室, 云南, 昆明, 650204
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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0253-2670 |
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学科
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中国医学 |
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文献收藏号
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CSCD:2872900
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