百蕊草的化学成分研究
Study on chemical constituents of Thesium chinensis
查看参考文献6篇
文摘
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目的研究百蕊草Thesium chinense的化学成分.方法采用反复柱色谱和制备性HPLC百蕊草的醋酸乙酯萃取物中分离得到5种化合物,通过理化和光谱分析鉴定其化学结构,并研究其抗氧化活性.结果自百蕊草的醋酸乙酯萃取物中分离得到5种黄酮苷类化合物,分别鉴定为:山柰素-3-O-葡萄糖苷(kaempferol-3-O-glucoside,Ⅰ),柚皮素-4-O-葡萄糖苷(naringenin-4-O-glucoside,Ⅱ),芹菜素-7-O-葡萄糖苷(apigenin-7-O-glucoside,Ⅲ),木犀草素-7-O-葡萄糖苷(1uteolin-7-O-glucoside,Ⅳ),芸香苷(rutinoside,Ⅴ).抗氧化实验结果表明,化合物Ⅰ的抗氧化作用最强,3个浓度中以1×10-mol/L作用最明显.结论化合物Ⅰ具有较强的抗氧化作用. |
其他语种文摘
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Object To study the chemical constituents of Thesium chinensis Turcz. and their antioxida-tion effects. Methods Isolation and purification were repeatedly carried out on gel column chromatogra-phy and preparative HPLC The structures were identified and elucidated by physicochemical properties and spectral analysis. Results Five compounds were elucidated as: kaempferol-3-O-glucoside (I), naringenin-4-O-glucoside (II), apigenin-7-O-glucoside (III),luteolin-7-O-glucoside (IV), rutinoside (V). It was found that kaempferol-3-O-glucoside (I) was the strongest one in the antioxidation experi-ment, its optimum concentration was 1*10~(-4) mol/L. Conclusion Compound I is the main antioxida-tion component isolated from T. chinensis. |
来源
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中草药
,2004,35(5):491-493 【核心库】
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关键词
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百蕊草
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黄酮苷
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抗氧化
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地址
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1.
安徽医科大学,生化教研室, 安徽, 合肥, 230032
2.
中国科学院昆明植物研究所,植物化学室, 云南, 昆明, 650204
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语种
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中文 |
文献类型
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研究性论文 |
ISSN
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0253-2670 |
学科
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中国医学 |
文献收藏号
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CSCD:1583062
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