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吉林产西洋参的皂苷成分研究
Studies on Saponin Constituents in Roots of Panax quinquefolium

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苏健 1   李海舟 2   杨崇仁 2  
文摘 目的:研究吉林产西洋参根中的皂苷成分。方法:西洋参根的甲醇提取物用氯仿和正丁醇萃取,正丁醇萃取物经硅胶和RP-8反相硅胶反复柱层析分离,得到纯化合物。通过谱学分析鉴定其结构。结果:分离得到10个单体皂苷,分别鉴定为24(R)-假人参皂苷RT_5(1),人参皂苷Rg_1(2),20(R)-人参皂苷Rg_3(3),24(R)-假人参皂苷F_(11)(4),人参皂苷Re(5),三七皂苷K(6),人参皂苷Rd(7),人参皂苷Rc(8),人参皂苷Rb_1(9),以及人参皂苷Rb_2(10)。结论:对吉林产西洋参的皂苷成分进行了较系统的化学研究,分离鉴定10个单体皂苷,其中,化合物1为首次从西洋参中分离得到。
其他语种文摘 Objective: To examine the saponins constituents in roots of Panax quinquefolium cultivated in China. Method: Themethanol extract from roots of P. quinquefolium cultivated in Jiling province of China was extracted by chloroform and nbutanol successively. Ten pure saponins were isolated from the n-butanol extract by silica gel and RP-8 reversed-phase column chromatography. Their structures were identified by means of spectral methods and compared with known compounds. Result: Ten saponins were isolated from P. quinquefolium. They were identified as ginsenoside Rgi (2), Re(5), Rd(7), Rc(8),. Rbi(9), Rb>2 (10), 24(i?)-ginsenoside Rg3(3), 24(R)-seudoginsenoside RT5(1), Fu(4) and notoginsenoside K(6), respectively. Conclusion: This work has elucidated the saponins constituents of P. quinquefolium cultivated in Jilin province of China and has shown that compound 1 was isolated from this plant for the first time.
来源 中国中药杂志 ,2003,28(9):830-833 【核心库】
关键词 西洋参 ; 皂苷 ; 人参皂苷
地址

1. 云南省药品检验所, 云南, 昆明, 650011  

2. 中国科学院昆明植物研究所, 云南, 昆明, 650204

语种 中文
文献类型 研究性论文
ISSN 1001-5302
学科 中国医学
文献收藏号 CSCD:1255701

参考文献 共 10 共1页

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引证文献 6

1 袁丁 竹节参化学成分及指纹图谱初步研究 中国药房,2009,20(18):1399-1401
被引 2

2 胡远浪 竹节参HPLC-ELSD指纹图谱和化学成分分析 中国中药杂志,2010,35(8):1009-1013
被引 6

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