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近红外光谱监测脑血氧饱和度与心脏骤停后自主循环恢复的关系:系统评价与Meta分析

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刘霜 1   张小明 2   乔文龙 3,4   陈沛权 3,4   周亮 3   刘朝晖 3   朱华栋 1 *   于学忠 1 *  
文摘 目的评估关于近红外光谱(near-infrared spectroscopy, NIRS )的测量值(初始值、平均值和最高值)在接受心肺复苏患者中预测自主循环恢复(return of spontaneous circulation,ROSC)方面的潜在作用。方法本研究根据PRISMA准则进行,检索Pubmed、Embase、Cochane Library、Web of science、Clinical gov、万方、维普、CNKI共8个数据库,收集所有在成人心脏骤停(cardiac arrest,CA)期间进行NIRS监测的观察性研究,并排除病例报告、综述和研究样本量小于5例的研究。两名作者评估纳入文章的质量并提取数据,结果效应使用标准化平均差(standardized mean difference, SMD )进行标准化。结果本综述纳入22项观察性研究,共计3 578例患者(304例患者发生院内CA, 3 274例患者发生院外CA )。研究发现患者的NIRS rSO_2初始值(SMD=0.72,95%CI: 0.50-0.94 )、平均值(SMD=1.12,95%CI: 0.86~1.37 )和最高值(SMD=1.86,95%CI:0.77~2.96)均与患者发生ROSC相关,ROSC组具有较高的脑氧饱和度测量值。不管是院外还是院内发生CA患者,其NIRS的平均rSO_2测定值与ROSC均有关联性(SMD=0.94, 95%CI:0.68~1.19;SMD=1.65, 95%CI: 0.85~2.45),院外发生CA患者与院内发生CA患者的平均rSO_2测定值与ROSC的关联差异无统计学意义(P=0.10)。结论不管是院内还是院外发生CA,恢复ROSC的患者在整个复苏过程中的NIRS脑血氧饱和度均显著高于非ROSC患者,其中平均NIRS rSO_2测定值与ROSC具有相对较强的关联。
来源 中华急诊医学杂志 ,2022,31(3):383-389 【核心库】
DOI 10.3760/cma.j.issn.1671-0282.2022.03.022
关键词 近红外光谱 ; 心脏骤停 ; 心肺复苏 ; 脑血氧饱和度
地址

1. 中国医学科学院北京协和医学院, 北京协和医院急诊科, 疑难重症及罕见病国家重点实验室, 北京, 100730  

2. 中国医学科学院北京协和医学院, 北京协和医院护理部, 北京, 100730  

3. 中国科学院西安光学精密机械研究所, 西安, 310063  

4. 中国科学院大学, 北京, 100049

语种 中文
文献类型 研究性论文
ISSN 1671-0282
学科 医药、卫生
基金 睿E(睿意)急诊医学研究专项基金
文献收藏号 CSCD:7176473

参考文献 共 31 共2页

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引证文献 1

1 胡海燕 胸外按压同步通气模式在猪心肺复苏模型中对脑组织氧合的作用 中华急诊医学杂志,2022,31(10):1373-1378
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