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基于甲状腺超声图像建立甲状腺乳头状癌中央区淋巴结转移人工智能诊断模型
A Thyroid Ultrasound Image-based Artificial Intelligence Model for Diagnosis of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma

查看参考文献28篇

李盈盈 1   孙文轩 2   廖献东 2   张明博 1   谢芳 1   陈东浩 2   张艳 1   罗渝昆 1 *  
文摘 目的基于甲状腺超声图像建立甲状腺乳头状癌中央区淋巴结转移人工智能诊断模型。方法回顾性分析2018年1至12月于中国人民解放军总医院第一医学中心行甲状腺切除及颈部中央区淋巴结清扫的309例甲状腺乳头状癌(PTC)患者的临床资料及超声图像,病理结果为金标准。所有病例被分为训练集(265例)、测试集(44例) 。基于深度学习方法建立甲状腺超声图像预测PTC患者中央区淋巴结转移的计算机辅助诊断系统。在测试集中评估该系统的诊断性能。结果在测试集中,本模型预测PTC患者中央区淋巴结转移的准确性、敏感性、特异性和受试者工作特征曲线下面积可达80%、76%、83%、0.794。结论基于深度学习的人工智能诊断模型可用于诊断甲状腺乳头状癌患者中央区淋巴结转移,可为临床选择治疗方案提供依据。
其他语种文摘 Objective To establish an artificial intelligence model based on B-mode thyroid ultrasound images to predict central compartment lymph node metastasis (CLNM) in patients with papillary thyroid carcinoma (PTC). Methods We retrieved the clinical manifestations and ultrasound images of the tumors in 309 patients with surgical histologically confirmed PTC and treated in the First Medical Center of PLA General Hospital from January to December in 2018. The datasets were split into the training set and the test set. We established a deep learning-based computer-aided model for the diagnosis of CLNM in patients with PTC and then evaluated the diagnosis performance of this model with the test set. Result The accuracy,sensitivity,specificity,and area under receiver operating characteristic curve of our model for predicting CLNM were 80%,76%,83%,and 0.794, respectively. Conclusion Deep learning-based radiomics can be applied in predicting CLNM in patients with PTC and provide a basis for therapeutic regimen selection in clinical practice.
来源 中国医学科学院学报 ,2021,43(6):911-916 【核心库】
DOI 10.3881/j.issn.1000-503X.13823
关键词 甲状腺乳头状癌 ; 中央区淋巴结转移 ; 超声 ; 人工智能
地址

1. 中国人民解放军总医院第一医学中心超声科, 北京, 100853  

2. 北京邮电大学人工智能学院, 北京, 100876

语种 中文
文献类型 研究性论文
ISSN 1000-503X
学科 临床医学
文献收藏号 CSCD:7126854

参考文献 共 28 共2页

1.  Mazzaferri E L. Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer. Clin Endocrinol Metab,2001,86(4):1447-1463 CSCD被引 53    
2.  Al-Saif O. Long-term efficacy of lymph node reoperation for persistent papillary thyroid cancer. J Clin Endocrinol Metab,2010,95(5):2187-2194 CSCD被引 12    
3.  Wang Y J. Nomogram for predicting central lymph node metastasis in papillary thyroid microcarcinoma: A retrospective cohort study of 8668 patients. Int J Surg,2018,55:98-102 CSCD被引 4    
4.  Lim Y C. Central lymph node metastases in unilateral papillary thyroid microcarcinoma. Br J Surg,2009,96(3):253-257 CSCD被引 24    
5.  Roh J L. Central cervical nodal metastasis from papillary thyroid microcarcinoma: Pattern and factors predictive of nodal metastasis. Ann Surg Oncol,2008,15(9):2482-2486 CSCD被引 18    
6.  Chen J. Conventional ultrasound, immunohistochemical factors and BRAF mutation in predicting central cervical lymph node metastasis of papillary thyroid carcinoma. Ultrasound Med Biol,2018,44(11):2296-2306 CSCD被引 14    
7.  Louise D. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg,2014,140(4):317-322 CSCD被引 75    
8.  Li N. Impact of enhanced detection on the increase in thyroid cancer incidence in the United States: Review of incidence trends by socioeconomic status within the surveillance,epidemiology,and end results registry, 1980-2008. Thyroid,2013,23(1):103-110 CSCD被引 15    
9.  Haugen B R. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid,2016,26(1):1-133 CSCD被引 774    
10.  Gilles R. Risk stratification of thyroid nodules on ultrasonography with the French TI-RADS: Description and reflections. Ultrasonography,2016,35(1):25-38 CSCD被引 14    
11.  Zhang M. Efficacy and safety of ultrasound-guided radiofrequency ablation for treating low-risk papillary thyroid microcarcinoma: A prospective study. Thyroid,2016,26(11):1581-1587 CSCD被引 30    
12.  Zhang M B. Ultrasound-guided radiofrequency ablation versus surgery for low-risk papillary thyroid microcarcinoma: Results of over 5 years'follow-up. Thyroid,2020,30(3):408-417 CSCD被引 2    
13.  Yan L. Long-term outcomes of radiofrequency ablation for unifocal low-risk papillary thyroid microcarcinoma: A large cohort study of 414 patients. Eur Radiol,2021,31(2):685-694 CSCD被引 6    
14.  Liu H. Local lymph node recurrence after central neck dissection in papillary thyroid cancers: A meta analysis. Eur Ann Otorhinolaryngol Head Neck Dis,2019,136(6):481-487 CSCD被引 1    
15.  Deng L. Regional recurrence rate of lymphnode-positive thyroid carcinoma after selective or comprehensive neck dissection. Oral Oncol,2019,90:147-149 CSCD被引 3    
16.  He K. Deep residual learning for image recognition,Jun 27-30,2016,2016 CSCD被引 1    
17.  Radosavovic R. Designing Network Design Spaces,Jun 16-18,2020,2020 CSCD被引 1    
18.  Tian X. Papillary thyroid carcinoma: an ultrasound-based nomogram improves the prediction of lymph node metastases in the central compartment. Eur Radiol,2020,30(11):5881-5893 CSCD被引 8    
19.  Lee J H. Deep learning-based computer-aided diagnosis system for localization and diagnosis of metastatic lymph nodes on ultrasound: A pilot study. Thyroid,2018,28(10):1332-1338 CSCD被引 9    
20.  Yeh M W. American Thyroid Association statement on preoperative imaging for thyroid cancer surgery. Thyroid,2015,25:3-14 CSCD被引 12    
引证文献 2

1 孙斌 超声新技术预测甲状腺乳头状癌颈部淋巴结转移的研究现状与展望 中国医学科学院学报,2023,45(4):672-676
CSCD被引 1

2 刘杰 甲状腺乳头状癌超声图像表现在预测颈部VI区淋巴结转移危险度的临床价值 中国耳鼻咽喉头颈外科,2024,31(7):470-473
CSCD被引 0 次

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