Recent progress in drug delivery
查看参考文献224篇
文摘
Drug delivery systems(DDS)are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. Its usual purpose to improve the pharmacological activities of therapeutic drugs and to overcome problems such as limited solubility, drug aggregation, low bioavailability, poor biodistribution, lack of selectivity, or to reduce the side effects of therapeutic drugs. During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields, such as pharmaceutical sciences, material sciences and biomedical sciences. This review provides a concise overview of current progress in this research area through its focus on the delivery strategies, construction techniques and specific examples. It is a valuable reference for pharmaceutical scientists who want to learn more about the design of drug delivery systems.
来源
Acta Pharmaceutica Sinica B
,2019,9(6):1145-1162 【核心库】
DOI
10.1016/j.apsb.2019.08.003
关键词
Pharmaceutics
;
Drug delivery system
;
Basic research
;
Application
;
Delivery strategy
地址
1.
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715
2.
School of Pharmaceutical Sciences, Peking University, Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems;; State Key Laboratory of Natural and Biomimetic Drugs, Beijing, 100191
3.
West China School of Pharmacy, Sichuan University, Sichuang Key Laboratory of Drug Targeting and Drug Delivery Systems, Chengdu, 610041
4.
Fudan University, Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai, 201203
5.
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203
6.
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016
7.
School of Pharmaceutical Sciences(Shenzhen), Sun Yat-sen University, Guangzhou, 510275
8.
School of Radiation Medicine and Protection, Soochow University, Suzhou, 215123
9.
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006
10.
School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030
11.
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850
语种
英文
文献类型
研究性论文
ISSN
2211-3835
学科
药学
基金
the Drug Innovation Major Project of China
文献收藏号
CSCD:6627754
参考文献 共
224
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