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Effects and mechanisms of Bacillus thuringiensis crystal toxins for mosquito larvae

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Zhang Qi 1   Hua Gang 2   Adang Michael J 2 *  
文摘 Bacillus thuringiensis is a Gram-positive aerobic bacterium that produces insecticidal crystalline inclusions during sporulation phases of the mother cell. The virulence factor, known as parasporal crystals, is composed of Cry and Cyt toxins. Most Cry toxins display a common 3-domain topology. Cry toxins exert intoxication through toxin activation, receptor binding and pore formation in a suitable larval gut environment. The mosquitocidal toxins of Bt subsp. israelensis (Bti) were found to be highly active against mosquito larvae and are widely used for vector control. Bt subsp. jegathesan is another strain which possesses high potency against broad range of mosquito larvae. The present review summarizes characterized receptors for Cry toxins in mosquito larvae, and will also discuss the diversity and effects of 3-D mosquitocidal Cry toxin and the ongoing research for Cry toxin mechanisms generated from investigations of lepidopteran and dipteran larvae.
来源 Insect Science ,2017,24(5):714-729 【核心库】
DOI 10.1111/1744-7917.12401
关键词 Bacillus thuringiensis ; Cry toxins ; mode of action ; mosquito ; receptors
地址

1. College of Plant Protection, Shenyang Agricultural University, Shenyang  

2. Department of Entomology, University of Georgia, USA, Athens

语种 英文
文献类型 综述型
ISSN 1672-9609
文献收藏号 CSCD:6092281

参考文献 共 175 共9页

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