Indoor Allergen Levels and Household Distributions in Nine Cities Across China
查看参考文献36篇
文摘
Objective Chinese allergic subjects have high levels of sensitization to house dust mite (HDM) and other indoor allergens. This study quantifies common indoor allergen levels in Chinese households. Methods Dust samples were collected from nine cities. Major allergens Der p 1 and Der f 1 from Dermatophagoides pteronyssinus and D. farinae, and specific antigens of Blomia tropicalis, Tyrophagus putrescentiae, Acarus siro, and cockroach species Blattella germanica and Periplaneta americana were measured by ELISA. Results HDM allergens were found in dust samples from bedding in 95% of the Chinese households. The median levels varied from <0.006 to 9.2 μg/g of dust, depending on the city. The percentages of households having HDM allergen levels associated with the risk of developing allergy sensitization and asthma were 65% and 25%, respectively. Specific antigens of the storage mite and cockroach were only found in samples from the southern and tropical regions of China. Levels of mite allergens were generally higher in samples from bedding compared to samples from the living room, even for storage mites, whereas levels of cockroach antigens were higher in the living room samples. Conclusion HDM allergens are present in bedding dust samples from most Chinese households. Cities in southern and central China have relatively high levels of HDM major allergens compared to cities in northern and western China. Antigens of storage mites and cockroaches are not as common as HDM allergens.
来源
Biomedical and Environmental Sciences
,2015,28(10):709-717 【核心库】
DOI
10.3967/bes2015.101
关键词
Dermatophagoides pteronyssinus
;
D. farinae
;
House dust mite
;
Indoor allergen
;
Storage mite
地址
1.
Research Asia Pacific, ALK, Guangdong, Guangzhou, 510230
2.
Department of Respiratory Medicine, the Affiliated Children's Hospital of Nanjing Medical University, Jiangsu, Nanjing, 210005
3.
the First Affiliated Hospital, Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangdong, Guangzhou, 510230
4.
ENT Department of Wuhan Union Hospital, Hubei, Wuhan, 430012
5.
ENT Department of Beijing Tongren Hospital, Beijing, 100730
6.
Allergology Department of Shenyang 202 Hospital, Liaoning, Shenyang, 110055
7.
Asthmatic Children’s Immunotherapy Center of People’s Hospital of Hainan Province, Hainan, Haikou, 570311
8.
Respiratory Department, Children's Hospital of Chongqing Medical University, Chongqing, 400014
9.
Department of Medical Science and Occupational and Environmental Medicine, University Hospital, Uppsala University, Sweden, Uppsala, 75105
语种
英文
文献类型
研究性论文
ISSN
0895-3988
学科
社会与环境
文献收藏号
CSCD:5563727
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