自闭症患者大脑语言功能的异常偏侧化研究进展
Researches on Atypical Lateralization of Autisms' Language Development
查看参考文献56篇
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文摘
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自闭症谱系障碍(autismspectrumdisorders,ASD)是一种广泛发展障碍,以社会交往障碍、言语和非言语交流缺陷、兴趣狭窄和行为刻板等为主要临床特征.本文简述了自闭症的核心症状———语言障碍,回顾了自1986年以来,对自闭症语言障碍神经机制的研究,从其大脑结构、功能不对称性及相关利手因素的影响三个方面,综述了自闭症语言功能的异常偏侧化领域的研究成果和进展,期望为自闭症语言障碍的鉴别与治疗提供帮助,并促进汉语背景下自闭症患者的语言功能偏侧化研究. |
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其他语种文摘
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Autismspectrumdisorders (ASD) is a widely developmental disabilities, with the main clinical features including barriers to social interaction, verbal and non-verbal communication defects, narrow interests and stereotyped behaviors. The present article aims to introduce some information about language impairment of autism, including relative researches published from 1986 to the current time on the neural mechanisms underlying autism's language impairment. This issue was addressed from brain structural, brain functional asymmetry, and the influence of handness, and at last, a summary was given based on the literatures, which is that the autism has an atypical right language lateralization both of structural and functional, there also exist available evidence that atypical handness is associated with poorer neurocognition or anomalous cerebral asymmetries. This article will be helpful for diagnosis and therapy to the autism in the future and will facilitate the research of ASDs under Chinese culture. |
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来源
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生物化学与生物物理进展
,2014,41(8):749-754 【核心库】
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DOI
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10.3724/sp.j.1206.2013.00296
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关键词
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自闭症(ASD)
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异常偏侧化
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颞上回
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额叶
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利手
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地址
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1.
中国科学院心理研究所, 中国科学院行为科学所重点实验室, 北京, 100101
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河北大学教育学院, 保定, 071002
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语种
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中文 |
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文献类型
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综述型 |
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ISSN
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1000-3282 |
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学科
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社会科学总论 |
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基金
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国家自然科学基金资助项目
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文献收藏号
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CSCD:5225509
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