Gender disparity in early death after ST-elevation myocardial infarction
查看参考文献25篇
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文摘
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Background Females with acute myocardial infarction (AMI) have a higher risk of adverse outcomes because of receiving less evidence-based medical care. Our aim was to investigate the gender disparity in early death after ST-elevation myocardial infarction (STEMI) in the current era. Methods A total of 1429 consecutive patients with STEMI in the Liaoning district were analyzed. We compared hospital care and cardiac event data by sex for in-patients with acute STEMI within 24 hours of symptom onset. Results In the emergency reperfusion group (n=754), in-hospital mortality occurred in 4.2% of the males and 11.2% of the females (P=0.001). In the non-emergency reperfusion group (n=675), in-hospital mortality occurred in 13.0% of the males and 22.9% of the females (P=0.001). Multivariate Logistic regression analysis revealed female sex as an independent risk factor of death for STEMI patients during hospitalization (OR=1.691, P=0.007). After controlling for patients who died within 24 hr after admission, female sex was no longer an independent risk factor (OR=1.409, P=0.259). Conclusion Female sex was an independent risk factor for in-hospital mortality of STEMI patients, which is explained by an excess of very early deaths. |
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来源
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Chinese Medical Journal
,2013,126(18):3481-3485 【核心库】
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DOI
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10.3760/cma.j.issn.0366-6999.20130381
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关键词
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myocardial infarction
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gender
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reperfusion
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mortality
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地址
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1.
Department of Cardiology, First Affiliated Hospital, Dalian Medical University, Liaoning, Dalian, 116011
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Department of Geriatrics, First Affiliated Hospital, Dalian Medical University, Liaoning, Dalian, 116011
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Department of Cardiology, Dandong Center Hospital, Liaoning, Dandong, 118000
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Department of Cardiology, First Affiliated Hospital, China Medical University, Liaoning, Shenyang, 110001
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语种
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英文 |
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文献类型
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研究性论文 |
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ISSN
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0366-6999 |
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学科
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内科学 |
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基金
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supported by a grant from Science and Technology Planning Project of Liaoning Province, China
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文献收藏号
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CSCD:4928333
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