帮助 关于我们

返回检索结果

Neuronal differentiation of adipose-derived stem cells and their transplantation for cerebral ischemia

查看参考文献56篇

Tian Guoping 1 *   Zhou Jin 1   Jinge Wang 1   Xu Bing 1   Li Li 1   Zhu Feng 1   Han Jian 1   Li Jianping 2   Zhang Siyang 3   Luo Xiaoguang 4  
文摘 OBJECTIVE:To review published data on the biological characteristics,differentiation and applications of adipose-derived stem cells in ischemic diseases.DATA RETRIEVAL:A computer-based online search of reports published from January 2005 to June 2012 related to the development of adipose-derived stem cells and their transplantation for treatment of cerebral ischemia was performed in Web of Science using the key words "adipose-derived stem cells","neural-like cells","transplantation","stroke",and "cerebral ischemia".SELECTION CRITERIA:The documents associated with the development of adipose-derived stem cells and their transplantation for treatment of cerebral ischemia were selected,and those published in the last 3-5 years or in authoritative journals were preferred in the same field.Totally 89 articles were obtained in the initial retrieval,of which 53 were chosen based on the inclusion criteria.MAIN OUTCOME MEASURES:Biological characteristics and induced differentiation of adipose-derived stem cells and cell transplantation for disease treatment as well as the underlying mechanism of clinical application.RESULTS:The advantages of adipose-derived stem cells include their ease of procurement,wide availability,rapid expansion,low tumorigenesis,low immunogenicity,and absence of ethical constraints.Preclinical experiments have demonstrated that transplanted adipose-derived stem cells can improve neurological functions,reduce small regions of cerebral infarction,promote angiogenesis,and express neuron-specific markers.The improvement of neurological functions was demonstrated in experiments using different methods and time courses of adipose-derived stem cell transplantation,but the mechanisms remain unclear.CONCLUSION:Further research into the treatment of ischemic disease by adipose-derived stem cell transplantation is needed to determine their mechanism of action.
来源 Neural Regeneration Research ,2012,7(25):1992-1999 【核心库】
DOI 10.3969/j.issn.1673-5374.2012.25.011
关键词 adipose-derived stem cells ; adipose stem cells ; differentiation ; adipose tissue ; neural-like cells ; transplantation ; stroke ; cerebral ischemia ; cerebrovascular disease ; stem cell therapy
地址

1. Department of Neurology,Shenyang First People’s Hospital, Liaoning, Shenyang, 110041  

2. Liaoning Blood Center, Liaoning, Shenyang, 110044  

3. College of Basic Medical Science,China Medical University, Liaoning, Shenyang, 110001  

4. Department of Neurology,First Affiliated Hospital of China Medical University, Liaoning, Shenyang, 110001

语种 英文
ISSN 1673-5374
学科 神经病学与精神病学
基金 supported by the Research Foundation of Shenyang Scientific Committee
文献收藏号 CSCD:4648170

参考文献 共 56 共3页

1.  Broderick J P. Guidelines for the management of spontaneous intracerebral hemorrhage: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke,1999,30(4):905-915 CSCD被引 31 次    
2.  Mendelow A D. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the international surgical trial in intracerebral haemorrhage (STICH): a randomised trial. Lancet,2005,365(9457):387-397 CSCD被引 89 次    
3.  Chang Y C. Regenerative therapy for stroke. Cell Transplant,2007,16(2):171-181 CSCD被引 11 次    
4.  Bang O Y. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol,2005,57(6):874-882 CSCD被引 49 次    
5.  Strem B M. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med,2005,54(3):132-141 CSCD被引 99 次    
6.  De Ugarte D A. Comparison of multi-lineage cells from human adipose tissue and bone marrow. Cells Tissues Organs,2003,174(3):101-109 CSCD被引 120 次    
7.  Zuk P A. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng,2001,7(2):211-228 CSCD被引 734 次    
8.  Aust L. Yield of human adipose-derived adult stem cells from liposuction aspirates. Cytotherapy,2004,6(1):7-14 CSCD被引 61 次    
9.  Winter A. Cartilage-like gene expression in differentiated human stem cell spheroids: a comparison of bone marrow-derived and adipose tissue-derived stromal cells. Arthritis Rheum,2003,48(2):418-429 CSCD被引 40 次    
10.  Ashjian P H. In vitro differentiation of human processed lipoaspirate cells into early neural progenitors. Plast Reconstr Surg,2003,111(6):1922-1931 CSCD被引 38 次    
11.  Brzoska M. Epithelial differentiation of human adipose tissue-derived adult stem cells. Biochem Biophys Res Commun,2005,330(1):142-150 CSCD被引 26 次    
12.  Gimble J. Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy,2003,5(5):362-369 CSCD被引 52 次    
13.  Planat-Benard V. Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives. Circulation,2004,109(5):656-663 CSCD被引 75 次    
14.  Mitchell J B. Immunophenotype of human adipose-derived stem cells: temporal changes in stromal-associated and stem cell-associated markers. Tiss Eng,2001,79(2):211-228 CSCD被引 2 次    
15.  Kang K. Neurogenesis of Rhesus adipose stromal cells. Cell Sci,2004,117:4289-4299 CSCD被引 16 次    
16.  Lee C H. CTGF directs fibroblast differentiation from human mesenchymal stem/stromal cells and defines connective tissue healing in a rodent injury model. J Clin Invest,2010,120(9):3340-3349 CSCD被引 17 次    
17.  Bianco P. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell,2008,2(4):313-319 CSCD被引 95 次    
18.  Ackema K B. Mesenchymal stem cells from different organs are characterized by distinct topographic Hox Codes. Stem Cells Dev,2008,17(5):979-992 CSCD被引 4 次    
19.  Dominici M. Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement. Cytotherapy,2006,8(4):315-317 CSCD被引 664 次    
20.  Kolf C M. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Arthritis Res Ther,2007,9:204 CSCD被引 39 次    
引证文献 2 篇

1 Zhou Fei Adipose-derived stem cells in stroke treatment: translational possibility and mechanism Chinese Medical Journal,2014,127(20):3657-3663
CSCD被引 0 次

2 Feng Zhichao Reduced graphene oxide-mediated magnetoelectric effect drives neural differentiation of mesenchymal stem cells Science China. Materials,2023,66(6):2504-2512
CSCD被引 0 次

显示所有2篇文献

论文科学数据集
PlumX Metrics
相关文献

 作者相关
 关键词相关
 参考文献相关

版权所有 ©2008 中国科学院文献情报中心 制作维护：中国科学院文献情报中心
地址：北京中关村北四环西路33号 邮政编码：100190 联系电话：(010)82627496 E-mail:cscd@mail.las.ac.cn 京ICP备05002861号-4 | 京公网安备11010802043238号