低强度半导体激光照射调节成纤维细胞时钟基因表达
Modulation of Low Intensity Laser Irradiation on Expression Suppression of Circadian Clock Genes in Cultured Fibroblasts
查看参考文献19篇
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文摘
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研究了低强度810nm半导体激光(LIDL)对肿瘤坏死因子α(TNF-α)抑制的NIH3T3成纤维细胞时钟基因表达的调节作用。马血清休克2h的细胞用质量浓度为10ng/mL的TNF-α孵育,分别用不同剂量的LIDL照射一次。结果表明LIDL可以调节TNF-α对NIH3T3成纤维细胞时钟基因表达的抑制作用,而且这种调节作用可能是通过烟酰胺腺嘌呤二核苷酸辅酶与其形式的比值(NAD+/NADH)和Ⅲ型组蛋白去乙酰化酶1(SIRT1)实现的。 |
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其他语种文摘
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The effects of low intensity 810 nm laser irradiation(LIDL)to the tumor necrosis factor(TNF)-α induced expression suppression of circadian clock genes in cultured NIH3T3 fibroblasts are investigated.The fibroblasts shocked by horse serum for 2 h are induced with TNF-α of 10 ng/mL,and then irradiated by different doses of LIDL once.The results show that TNF-α induced inhibition effect of the circadian clock gene expression can be modulated by LIDL,which may be mediated by nicotinamide adenine dinucleotide/ reduced form of nicotinamide adenine dinucleotid(NAD+/NADH)and sirtuin 1(SIRT1) |
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来源
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中国激光
,2011,38(8):0804001-1-0804001-6 【核心库】
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关键词
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生物光学
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低强度激光
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时钟基因
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组蛋白去乙酰化酶
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地址
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1.
华南师范大学体育科学学院激光运动医学实验室和民族健康与体质研究中心, 广东, 广州, 510006
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中国科学院心理研究所, 北京, 100101
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语种
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中文 |
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文献类型
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研究性论文 |
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ISSN
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0258-7025 |
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学科
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生物物理学 |
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基金
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国家自然科学基金资助课题
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文献收藏号
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CSCD:4282636
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参考文献 共
19
共1页
|
|
1.
Science News. Breakthrough of the year.The runners-up.
Science,1998,282(5397):2157-2161
|
CSCD被引
1
次
|
|
|
|
|
2.
A Balsalobre. A serum shock induces circadian gene expression in mammalian tissue culture cells.
Cell,1998,93(6):929-937
|
CSCD被引
24
次
|
|
|
|
|
3.
S S Campbell. Extraocular circadian phototransduction in humans.
Science,1998,279(5349):396-399
|
CSCD被引
6
次
|
|
|
|
|
4.
D J Skene. Circadian rhythm sleep disorders in the blind and their treatment with melatonin.
Sleep Med,2007,8(6):651-655
|
CSCD被引
2
次
|
|
|
|
|
5.
J S O′Neill. Circadian clocks in human red blood cells.
Nature,2011,469(7331):498-503
|
CSCD被引
1
次
|
|
|
|
|
6.
K P Wright. Absence of circadian phase resetting in response to bright light behind the knees.
Science,2002,297(5581):571
|
CSCD被引
5
次
|
|
|
|
|
7.
N Lane. Cell biology:power games.
Nature,2006,443(7114):901-903
|
CSCD被引
13
次
|
|
|
|
|
8.
Liu T C Y. Homeostatic photobiomodulation.
Front.Optoelectron.China,2009,2(1):1-8
|
CSCD被引
7
次
|
|
|
|
|
9.
刘承宜. 组蛋白去乙酰化酶介导的动物非视觉细胞的光康复机制.
中国激光,2009,36(10):2485-2492
|
CSCD被引
6
次
|
|
|
|
|
10.
刘承宜.
激光功能医学及其应用,2011:16-420
|
CSCD被引
1
次
|
|
|
|
|
11.
刘承宜. 鼻腔内低强度激光照射疗法的机理.
中国激光,2009,36(11):2799-2804
|
CSCD被引
8
次
|
|
|
|
|
12.
T Finkel. Recent progress in the biology and physiology of sirtuins.
Nature,2009,460(7255):587-591
|
CSCD被引
68
次
|
|
|
|
|
13.
G Cavadini. TNF-alpha suppresses the expression of clock genes by interfering with Ebox-mediated transcription.
Proc.Natl.Acad.Sci.USA,2007,104(31):12843-12848
|
CSCD被引
12
次
|
|
|
|
|
14.
K Oh-hashi. Intracellular calcium mobilization induces period genes via MAP kinese pathways in NIH3T3cells.
FEBS Lett,2002,56(1/3):101-105
|
CSCD被引
1
次
|
|
|
|
|
15.
Jt Rodgers. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
Nature,2005,434(7029):113-118
|
CSCD被引
101
次
|
|
|
|
|
16.
K Menzel. Kinetic,dynamic,and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture:IV.Enzymes and fluxes of pyruvate metabolism.
Biotechnol.Bioeng,1998,60(5):617-626
|
CSCD被引
13
次
|
|
|
|
|
17.
刘承宜. 激光或单色光引起非视觉细胞信号转导的现象与机理.
中国激光,2009,36(9):2251-2256
|
CSCD被引
3
次
|
|
|
|
|
18.
M Hübscher. Laser needle acupuncture at Neiguan(PC6)does not mediate heart rate variability in young,healthy men.
Photomed.Laser Surg,2007,25(1):21-25
|
CSCD被引
1
次
|
|
|
|
|
19.
Wu J H. Study of autonomic nervous activity of night shift workers treated with laser acupuncture.
Photomed.Laser Surg,2009,27(2):273-279
|
CSCD被引
1
次
|
|
|
|
|
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