Nutrition support in surgical patients with colorectal cancer
查看参考文献39篇
文摘
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AIM: To review the application of nutrition support in patients after surgery for colorectal cancer, and to propose appropriate nutrition strategies. METHODS: A total of 202 consecutive surgical patients admitted to our hospital with a diagnosis of colon cancer or rectal cancer from January 2010 to July 2010, meeting the requirements of Nutrition Risk Screening 2002, were enrolled in our study. Laboratory tests were performed to analyze the nutrition status of each patient, and the clinical outcome variables, including postoperative complications, hospital stay, cost of hospitalization and postoperative outcome, were analyzed. RESULTS: The "non-risk" patients who did not receive postoperative nutrition support had a higher rate of postoperative complications than patients who received postoperative nutrition support (2.40 ± 1.51 vs 1.23 ± 0.60, P = 0.000), and had a longer postoperative hospital stay (23.00 ± 15.84 d vs 15.27 ± 5.89 d, P = 0.009). There was higher cost of hospitalization for patients who received preoperative total parenteral nutrition (TPN) than for patients who did not receive preoperative TPN(62 713.50 ± 5070.66 RMB Yuan vs 43178.00 ± 3596.68 RMB Yuan, P = 0.014). Applying postoperative enteral nutrition significantly shortened postoperative fasting time(5.16 ± 1.21 d vs 6.40 ± 1.84 d, P = 0.001) and postoperative hospital stay (11.92 ± 4.34 d vs 15.77 ± 6.03 d, P = 0.002). The patients who received postoperative TPN for no less than 7 d had increased serum glucose levels(7.59 ± 3.57 mmol/L vs 6.48 ± 1.32 mmol/L, P = 0.006) and cost of hospitalization (47 724.14 ± 16 945.17 Yuan vs 38 598.73 ± 8349.79 Yuan, P = 0.000). The patients who received postoperative omega-3 fatty acids had a higher rate of postoperative complications than the patients who did not (1.33 ± 0.64 vs 1.13 ± 0.49, P = 0.041). High level of serum glucose was associated with a high risk of postoperative complications of infection. CONCLUSION: Appropriate and moderate nutritional intervention can improve the postoperative outcome of colorectal cancer patients |
来源
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World Journal of Gastroenterology
,2011,17(13):1779-1786 【核心库】
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关键词
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Nutritional support
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Nutrition assessment
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Colorectal cancer
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Surgery
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Prognosis
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地址
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Depart ment of Surgery, Shengjing Hospital, China Medical University, Liaoning, Shenyang, 110004
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语种
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英文 |
文献类型
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研究性论文 |
ISSN
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1007-9327 |
学科
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内科学 |
基金
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Postgraduate Scientific Research Fund of Shengjing Hospital, China Medical University
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文献收藏号
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CSCD:4190064
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参考文献 共
39
共2页
|
1.
Center MM. Worldwide variations in colorectal cancer.
CA Cancer J Clin,2009,59:366-378
|
CSCD被引
41
次
|
|
|
|
2.
Gellad ZF. Colorectal cancer: national and international perspective on the burden of disease and public health impact.
Gastroenterology,2010,138:2177-2190
|
CSCD被引
4
次
|
|
|
|
3.
Osland EJ. Early postoperative feeding in resectional gastrointestinal surgical cancer patients.
World J Gastrointest Oncol,2010,2:187-191
|
CSCD被引
5
次
|
|
|
|
4.
Planas M. Guidelines for colorectal cancer: effects on nutritional intervention.
Clin Nutr,2007,26:691-697
|
CSCD被引
1
次
|
|
|
|
5.
Johansson U. Clinical nutrition in medical gastroenterology: room for improvement.
Clin Nutr,2009,28:129-133
|
CSCD被引
1
次
|
|
|
|
6.
Bozzetti F. The ESPEN clinical practice Guidelines on Parenteral Nutrition: present status and perspectives for future research.
Clin Nutr,2009,28:359-364
|
CSCD被引
9
次
|
|
|
|
7.
Kondrup J. ESPEN guidelines for nutrition screening 2002.
Clin Nutr,2003,22:415-421
|
CSCD被引
294
次
|
|
|
|
8.
Edge SB.
AJCC cancer staging manual. 7th ed,2010:143-464
|
CSCD被引
4
次
|
|
|
|
9.
Tian J. Effects of nutritional and psychological status in gastrointestinal cancer patients on tolerance of treatment.
World J Gastroenterol,2007,13:4136-4140
|
CSCD被引
2
次
|
|
|
|
10.
Ottery FD. Cancer cachexia: prevention, early diagnosis, and management.
Cancer Pract,1994,2:123-131
|
CSCD被引
7
次
|
|
|
|
11.
Seidner DL. Nutritional issues in the surgical patient.
Cleve Clin JMed,2006,73(Suppl 1):S77-S81
|
CSCD被引
1
次
|
|
|
|
12.
Bozzetti F. Nutritional support and tumour growth in humans: a narrative review of the literature.
Clin Nutr,2009,28:226-230
|
CSCD被引
2
次
|
|
|
|
13.
Wu GH. Perioperative artificial nutrition in malnourished gastrointestinal cancer patients.
World J Gastroenterol,2006,12:2441-2444
|
CSCD被引
2
次
|
|
|
|
14.
McClave SA. Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.).
JPEN J Parenter Enteral Nutr,2009,33:277-316
|
CSCD被引
108
次
|
|
|
|
15.
. Clinical Guidelines for the Use of Parenteral and Enteral Nutrition in Adult and Pediatric Patients, 2009.
JPEN J Parenter Enteral Nutr,2009,33:255-259
|
CSCD被引
9
次
|
|
|
|
16.
Braga M. ESPEN Guidelines on Parenteral Nutrition: surgery.
Clin Nutr,2009,28:378-386
|
CSCD被引
43
次
|
|
|
|
17.
August DA. A.S.P.E.N. clinical guidelines: nutrition support therapy during adult anticancer treatment and in hematopoietic cell transplantation.
JPEN J Parenter Enteral Nutr,2009,33:472-500
|
CSCD被引
24
次
|
|
|
|
18.
Schwegler I. Nutritional risk is a clinical predictor of postoperative mortality and morbidity in surgery for colorectal cancer.
Br J Surg,2010,97:92-97
|
CSCD被引
21
次
|
|
|
|
19.
Salvino RM. Perioperative nutrition support: who and how.
Cleve Clin J Med,2004,71:345-351
|
CSCD被引
1
次
|
|
|
|
20.
Karlsson S. Early assessment of nutritional status in patients scheduled for colorectal cancer surgery.
Gastroenterol Nurs,2009,32:265-270
|
CSCD被引
3
次
|
|
|
|
|