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抑郁症情绪认知加工中的特征负激活
Features of Deactivation of Depression in Emotional Cognitive Tasks

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马莹华 1   冯洪波 2   唐一源 1   张晔 3   李长军 1  
文摘 目的:探讨抑郁症患者在情绪认知任务状态下的负激活变化规律.方法:选取9例确诊抑郁症患者和9例年龄相匹配的健康被试,以情绪图片判别作为刺激任务,比较两组被试在任务状态下负激活的差别.统计分析采用SPM5软件包完成.结果:相对于健康被试组,抑郁症患者组表现出更为显著的全脑负激活模式,但后扣带回负激活出现特征缺失.结论:抑郁症患者在执行情绪认知任务时,脑内出现更大的资源重分配过程,并具有特异性.
其他语种文摘 Objective: To investigate the deactivation of the depressive patients in the emotional cognitive tasks. Methods: Nine diagnosed depressive patients and nine age-matched healthy subjects completed the tasks requiring emo-tional picture processing. The deactivation of the two groups in the tasks was analyzed by SPM5 package. Results: Com-pared with healthy subjects group, deactivation of depressive patients group was more apparent in the whole brain, espe-cially in the cingulate gyms, but not in the posterior cingulate gyms. Conclusion: The reallocation of brain resources in the depressive patients group during emotional cognitive tasks is affected by the cognitive disfunction, resulting in abnor-mal deactivation.
来源 中国临床心理学杂志 ,2009,17(2):191-193 【扩展库】
关键词 抑郁症 ; 负激活 ; 功能磁共振成像(fMRI)
地址

1. 大连理工大学,神经信息学研究所, 辽宁, 大连, 116024  

2. 大连医科大学附属第一医院,核医学科, 辽宁, 大连, 116011  

3. 深圳先进技术研究院, 广东, 深圳

语种 中文
文献类型 研究性论文
ISSN 1005-3611
学科 基础医学
基金 国家自然科学基金 ;  国家教育部新世纪优秀人才支持计划 ;  大连理工大学人文社会科学研究基金
文献收藏号 CSCD:3738390

参考文献 共 16 共1页

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引证文献 1

1 刘潇楠 国际情绪图片系统的本土化研究:在中国大学生群体中的评定 中国临床心理学杂志,2009,17(6):687-689,692
CSCD被引 14

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