抑郁症情绪认知加工中的特征负激活
Features of Deactivation of Depression in Emotional Cognitive Tasks
查看参考文献16篇
文摘
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目的:探讨抑郁症患者在情绪认知任务状态下的负激活变化规律.方法:选取9例确诊抑郁症患者和9例年龄相匹配的健康被试,以情绪图片判别作为刺激任务,比较两组被试在任务状态下负激活的差别.统计分析采用SPM5软件包完成.结果:相对于健康被试组,抑郁症患者组表现出更为显著的全脑负激活模式,但后扣带回负激活出现特征缺失.结论:抑郁症患者在执行情绪认知任务时,脑内出现更大的资源重分配过程,并具有特异性. |
其他语种文摘
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Objective: To investigate the deactivation of the depressive patients in the emotional cognitive tasks. Methods: Nine diagnosed depressive patients and nine age-matched healthy subjects completed the tasks requiring emo-tional picture processing. The deactivation of the two groups in the tasks was analyzed by SPM5 package. Results: Com-pared with healthy subjects group, deactivation of depressive patients group was more apparent in the whole brain, espe-cially in the cingulate gyms, but not in the posterior cingulate gyms. Conclusion: The reallocation of brain resources in the depressive patients group during emotional cognitive tasks is affected by the cognitive disfunction, resulting in abnor-mal deactivation. |
来源
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中国临床心理学杂志
,2009,17(2):191-193 【扩展库】
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关键词
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抑郁症
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负激活
;
功能磁共振成像(fMRI)
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地址
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1.
大连理工大学,神经信息学研究所, 辽宁, 大连, 116024
2.
大连医科大学附属第一医院,核医学科, 辽宁, 大连, 116011
3.
深圳先进技术研究院, 广东, 深圳
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语种
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中文 |
文献类型
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研究性论文 |
ISSN
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1005-3611 |
学科
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基础医学 |
基金
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国家自然科学基金
;
国家教育部新世纪优秀人才支持计划
;
大连理工大学人文社会科学研究基金
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文献收藏号
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CSCD:3738390
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参考文献 共
16
共1页
|
1.
Miller A. Task-dependent changes in frontal brain asymmetry:Effects of incentive cues,outcome expectancies,and motor responses.
Psychophysiology,2001,38(3):500-511
|
CSCD被引
1
次
|
|
|
|
2.
Austin MP. Single photon emission tomography with 99mTc-exametazime in major depression and the pattern of brain activity underlying the psychotic/neurotic continuum.
Journal of Affective Disorders,1992,26(1):31-43
|
CSCD被引
4
次
|
|
|
|
3.
Gonul AS. The regional cerebral blood flow changes in major depressive disorder with and without psychotic features.
Prog NeurnpsychopharmacolBiol Psychiatry,2004,28(6):1015-1021
|
CSCD被引
6
次
|
|
|
|
4.
汤艳清. 抑郁症的脑结构影像学改变及其机制的研究进展.
中国临床心理学杂志,2005,13(3):366-369
|
CSCD被引
12
次
|
|
|
|
5.
Mazoyer B. Cortical networks for working memory and executive functions sustain the conscious resting state in man.
Brain Research Bulletin,2001,54(3):287-298
|
CSCD被引
50
次
|
|
|
|
6.
Raichle ME. A default mode of brain function.
Proceedings of the National Academy of Sciences(USA),2001,98(2):676-682
|
CSCD被引
359
次
|
|
|
|
7.
Kennedy DP. Failing to deactivate:Resting functional abnormalities in autism.
Proceedings of the National Academy of Sciences(USA),2006,103(21):8275-8280
|
CSCD被引
12
次
|
|
|
|
8.
Wang L. Depressive Stateand Disease-Related Alterations in Neural Responses to Affective and Executive Challenges in Geriatric Depression.
American Journal of Psychiatry,2008,165(7):863-871
|
CSCD被引
4
次
|
|
|
|
9.
Greicius MD. Functional connectivity in the resting brain:A network analysis of the default mode hypothesis.
Proceedings of the National Academy of Sciences(USA),2003,100(1):253-258
|
CSCD被引
185
次
|
|
|
|
10.
Mckiernan KA. A parametric manipulation of factors affecting task-induced deactivation in functional neuroimaging.
Journal of Cognitive Neuroscience,2003,15(3):394-408
|
CSCD被引
22
次
|
|
|
|
11.
Shulman GL. Common blood flow changes across visual tasks,1.Increases in subeortical structures and cerebellum but not in nonvisual cortex.
Journal of Cognitive Neurnscience,1997,9(5):624-647
|
CSCD被引
37
次
|
|
|
|
12.
Shulman GL. Common blood flow changes across visual tasks,2.Decreases in cerebral cortex.
Journal of Cognitive Neuroscience,1997,9(5):648-663
|
CSCD被引
37
次
|
|
|
|
13.
冯洪波. 数字加和任务时的脑内负激活研究.
科学通报,2007,11:1280-1284
|
CSCD被引
3
次
|
|
|
|
14.
靳静. 探测静息状态大脑活动的关键区域.
自然科学进展,2007(5)
|
CSCD被引
1
次
|
|
|
|
15.
Drevets WC. Suppression of Regional Cerebral Blood during Emotional venus Higher Cognitive Implications for Interactions between Emotion and Cognition.
Cognition and Emotion,1998,12:353-385
|
CSCD被引
3
次
|
|
|
|
16.
Vogt BA. Functional heterogeneity in cingnlate cortex:The anterior executive and posterior evaluative regions.
Cerebral Cortex,1992,2(6):435-443
|
CSCD被引
23
次
|
|
|
|
|