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文摘
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A new neophysalin, named 5α-hydroxy-25,27-dihydro-4,7-didehydro-7-deoxyneophysalin A(1), along with three other known neophysalins (2-4) were isolated from the calyxes of Physalis alkekengi L. var.francheti (Mast.) Makino. The structure of 1 was determined by means of ID and 2D NMR, UV, IR and mass spectra. Compound 1 displayed potent cytotoxicities in vitro against PC-3 and LNCaP cell lines. |
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来源
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Chinese Chemical Letters
,2009,20(11):1327-1330 【核心库】
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DOI
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10.1016/j.cclet.2009.06.005
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关键词
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Physalis alkekengi vat francheti
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Neophysalin
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Cytotoxicity
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地址
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1.
School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University, Key Laboratory of Standardization of Chinese Medicines of Ministry of Education Institute of Chinese Materia Medica, Liaoning, Shenyang, 110016
2.
Shanghai University of Traditional Chinese Medicine, Key Laboratory of Standardization of Chinese Medicines of Ministry of Education Institute of Chinese Materia Medica, Shanghai, 201203
3.
School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University, Liaoning, Shenyang, 110016
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语种
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英文 |
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文献类型
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研究性论文 |
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ISSN
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1001-8417 |
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学科
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化学 |
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文献收藏号
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CSCD:3719908
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