|
Inhibitory Effect of Cantharidin on Proliferation of A549 Cells
查看参考文献10篇
文摘
|
Objective:To study the inhibition of Cantharidin against the proliferation of human lung cancer A549 cells and its mechanism.Methods:MTT assay was employed to determine the inhibition of Cantharidin against proliferation of A549 cells and flow Cytometry was applied to analyze A549 cell cycle and the effect of Cantharidin on cell cycle.Results:Cantharidin showed inhibition against the proliferation of A549 cells,and the inhibition was mediated by blocking A549 cell cycle at G2/M phase significantly.Conclusion:Cantharidin exhibits inhibition against the proliferation of human lung cancer A549 cells. |
来源
|
Chinese Journal of Cancer Research
,2007,19(4):283-286 【核心库】
|
关键词
|
Cantharidin(CTD)
;
Inhibition
;
Human lung cancer cells A549
|
地址
|
Cancer Research Institute;First Affiliated Hospital;China Medical University, Shenyang, 110001
|
语种
|
英文 |
文献类型
|
研究性论文 |
ISSN
|
1000-9604 |
学科
|
肿瘤学 |
文献收藏号
|
CSCD:3134518
|
参考文献 共
10
共1页
|
1.
Sun ZX. The studies of CTD and Norcantharidin induced HEL, human erythroleukemia K562 apoptosis.
J Anat(in Chin),2000,31:56-60
|
CSCD被引
1
次
|
|
|
|
2.
Kerr JF. Apoptosis, its significance in cancer and cancer therapy.
Cancer,1994,73:3108
|
CSCD被引
2
次
|
|
|
|
3.
Hartwell L. Cell cycle control and cancer.
Science,1994,266:1820-1828
|
CSCD被引
2
次
|
|
|
|
4.
Blagosklonny MV. Exploiting cancer cell cycling for selective protection of normal cell.
Cancer Res,2001,61:4301-4305
|
CSCD被引
13
次
|
|
|
|
5.
Roberts JR. Development of polyploidization in taxol resistant human leukemia cells in vitro.
Cancer Res,1990,50:710-716
|
CSCD被引
7
次
|
|
|
|
6.
Sherr CJ. The pezcoler lecture:Cancer cell-cycles revisited.
Cancer Res,2000,60:3689-3695
|
CSCD被引
39
次
|
|
|
|
7.
Li FZ. Control of apoptosis and mitotic spindle checkpoint by Survivin.
Nature,1998,396:580-584
|
CSCD被引
6
次
|
|
|
|
8.
Li B. Advances in basic and clinical studies of norcantharidin.
Chin Tradit Herbs Drugs(in Chin),2002,33:184-185
|
CSCD被引
3
次
|
|
|
|
9.
Jin W. The effects of canthacidiu on HL-60 and QGY7703 cell line.
Acta Chin Med Pharmacal,2001,29:42-43
|
CSCD被引
5
次
|
|
|
|
10.
Jiang LH. Research progress on Mylabris.
Herald Med,2004,23:385-386
|
CSCD被引
1
次
|
|
|
|
|
|